vegf — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T71944	FGF/PDGF/VEGF RTK Inhibitor
	FGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of h...
T8496	MAZ51		Apoptosis , VEGFR
	MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.		Apoptosis , VEGFR
T8574	SPHINX		Others
	SPHINX is a new generation inhibitor of SPRK1		Others
T4288	HVEGF-IN-1		VEGFR
	hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.		VEGFR
T15102	Dexamethasone palmitate	DXP	Glucocorticoid Receptor
	Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexamethasone palmitate is a glucocorticoid receptor agonist and an...		Glucocorticoid Receptor
T8973	HS-1793		Others
	HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model		Others
T9715	Aplidine		SARS-CoV , DNA/RNA Synthesis
	Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM).		SARS-CoV , DNA/RNA Synthesis
T9928	Ranibizumab		VEGFR
	Ranibizumab is a humanized monoclonal antibody fragment designed to target and inhibit vascular endothelial growth factor (VEGF), including VEGF110, VEGF121, and VEGF165. Ranibizumab's ability to selectively target and n...		VEGFR
T0463	Loxoprofen	Loxoprofene,Loxoprofeno,Koloxo	COX
	Loxoprofen (Koloxo) is an anti-inflammatory non-steroidal medicine.		COX
T8657	KYP-2047		Others
	KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.		Others
T6182	Tirofiban	L700462,Aggrastat,MK383	Integrin
	Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.		Integrin
T1152	Albendazole	SKF-62979	HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
	Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
T2537	Tirofiban hydrochloride monohydrate	Tirofiban Hydrochloride,MK-383 Hydrochloride	ATPase , Integrin
	Tirofiban hydrochloride monohydrate (MK-383 Hydrochloride) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.		ATPase , Integrin
TWA2417	Sodium taurocholate	Taurocholate Sodium	Others
	Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and...		Others
T72924	VEGFR-3-IN-1		VEGFR
	VEGFR-3-IN-1 is a novel potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM.VEGFR-3-IN-1 possesses antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of ...		VEGFR
T37078	VEGFR-2-IN-6		VEGFR
	VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].		VEGFR
T9979	VEGFR-2-IN-29		VEGFR
	VEGFR-2-IN-29 is a VEGFR2 inhibitor.		VEGFR
T10123	VEGFR-2-IN-9	KDR-in-4	VEGFR
	VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.		VEGFR
T61899	VEGFR2-IN-1		VEGFR
	VEGFR2-IN-1 is a selective and potent VEGFR2 inhibitor with antitumor activity that inhibits cell proliferation and migration and can be used in the study of breast cancer.		VEGFR
T2056	VEGFR-2-IN-5	2, 4-Pyrimidinediamine with linker,UNC0064-12,2,4-Pyrimidinediamine with linker	VEGFR
	VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.		VEGFR