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Search Result

Search Results for " urokinase "

Targets

OX Receptor

26

Compounds

1

Natural Products

29

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T3722 MK-1064 Urokinase inhibitor 1,MK 1064 OX Receptor
MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).
T73701 Urokinase (peptidolytic)
Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in t...
T13408 ZK824190 Others , Serine Protease
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively).
T8362 Benzamidine hydrochloride Benzamidine HCl Serine/threonin kinase , Serine Protease
Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).
T22600 BC 11 hydrobromide Others
The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.
T21703 4-Chlorophenylguanidine hydrochloride Others
4-Chlorophenylguanidine hydrochloride is a potent inhibitor of urokinase selectivity.
T13257 Upamostat PAI-1 , Serine/threonin kinase , Serine Protease
Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.
TP2338L Cenupatide acetate Cenupatide acetate(1006388-38-0 Free base) Others
Cenupatide acetate is an urokinase plasminogen activator receptor (uPAR) inhibitor for treating disorders associated altered cell migration, such as cancer.
T60248 4-Aminobenzamidine dihydrochloride p-Aminobenzamidine dihydrochloride Serine Protease
4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type plasminogen activator (uPA) (K i =82 μM). 4-Aminobenzamidine can inh...
T26629 Angstrom6 A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide PAI-1
Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade and abrogates the downstream effects.Angstrom6 has antitumor a...
T13251 UKI-1 UKI-1C Others
UKI-1 is a urokinase-type plasminogen activator system synthetic inhibitor.
T30911 Chromozym U
Chromozym U can be used as a chromogenic substrate test for urokinase in Shigella.
T69751 UK-356202
UK-356,202 is a potent and selective urokinase-type plasminogen activator (Ki = 37 nM). Urokinase plasminogen activator (uPA, urokinase) is a trypsinlike serine protease and a therapeutical target for many cancer types, ...
T70927 UCD74A HCl
UCD74A HCl is a cell impermeant homolog of UCD38B, inhibitor of uPA (urokinase plasminogen activator).
T13409 ZK824859 Others
ZK824859 is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).
T22451 UK-371804 HCl Serine Protease
UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-fold versus plasmin and 4000-fold versus tPA).
T35931 GGACK (hydrochloride)
GGACK is an inhibitor of urokinase-type plasminogen activator (uPA) and factor Xa (Kis = 1.8 and 8.7 μM, respectively).1,2 1.Kettner, C., and Shaw, E.The susceptibility of urokinase to affinity labeling by peptides of ar...
T13409L ZK824859 hydrochloride (2271122-53-1 free base) ZK824859 hydrochloride Others
ZK824859 hydrochloride is an oral available and selective inhibitor of urokinase plasminogen activator (uPA)(IC50s of 79 nM, 1580 nM and 1330 nM for human uPA, tPA, and plasmin, respectively).
TP2338 Cenupatide UPARANT,Cenupatide trifluoroacetic acid salt,Ac-Arg-Aib-Arg-α(Me)Phe-NH2)
Cenupatide is a urokinase plasminogen activator receptor (uPAR) inhibitor. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of STZ-induced diabetes. Cenupa...
T41085 UK122 UK122
UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA),...
T69028 CJ-463
CJ-463 is a potent ans selective uPA inhibitor. Treatment with CJ-463 resulted in a significant inhibition of primary tumor growth, with the highest efficacy seen in the 100 mg/kg group. Urokinase (uPA) plays a crucial r...
T62961 ZK824859 hydrochloride
ZK824859 hydrochloride is a selective, orally active inhibitor of urokinase-type fibrinogen activator (uPA) with IC50 values of 79 nM, 1580 nM and 1330 nM for human uPA, tPA and fibrin, respectively.
T35579 PKSI-527
PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 μM, respect...
T62731 ZK824190 hydrochloride
ZK824190 hydrochloride is a selective, orally active urokinase-type fibrinogen activator (uPA) inhibitor that acts on uPA (IC50: 237 nM), tPA (IC50: 1600 nM) and Plasmin (IC50: 1850 nM). hydrochloride can be used in stud...
T80859 Vitronectin
Vitronectin, a multifunctional glycoprotein found in blood and the extracellular matrix, interacts with glycosaminoglycans, collagen, plasminogen, and the urokinase-receptor, in addition to stabilizing the inhibitory con...
T78018 Plasminogen
Plasminogen is a zymogen secreted as a precursor protein that, when cleaved by urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA), is converted into plasmin. Plasmin is a protease with broad spec...

Compounds

MK-1064
T3722
Synonym: Urokinase inhibitor 1,MK 1064
Target: OX Receptor
Urokinase (peptidolytic)
T73701
Synonym:
Target:
ZK824190
T13408
Synonym:
Target: Others, Serine Protease
Benzamidine hydrochloride
T8362
Synonym: Benzamidine HCl
Target: Serine/threonin kinase, Serine Protease
BC 11 hydrobromide
T22600
Synonym:
Target: Others
4-Chlorophenylguanidine hydrochloride
T21703
Synonym:
Target: Others
Upamostat
T13257
Synonym:
Target: PAI-1, Serine/threonin kinase, Serine Protease
Cenupatide acetate
TP2338L
Synonym: Cenupatide acetate(1006388-38-0 Free base)
Target: Others
4-Aminobenzamidine dihydrochloride
T60248
Synonym: p-Aminobenzamidine dihydrochloride
Target: Serine Protease
Angstrom6
T26629
Synonym: A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide
Target: PAI-1
UKI-1
T13251
Synonym: UKI-1C
Target: Others
Chromozym U
T30911
Synonym:
Target:
UK-356202
T69751
Synonym:
Target:
UCD74A HCl
T70927
Synonym:
Target:
ZK824859
T13409
Synonym:
Target: Others
UK-371804 HCl
T22451
Synonym:
Target: Serine Protease
GGACK (hydrochloride)
T35931
Synonym:
Target:
ZK824859 hydrochloride (2271122-53-1 free base)
T13409L
Synonym: ZK824859 hydrochloride
Target: Others
Cenupatide
TP2338
Synonym: UPARANT,Cenupatide trifluoroacetic acid salt,Ac-Arg-Aib-Arg-α(Me)Phe-NH2)
Target:
UK122
T41085
Synonym: UK122
Target:
CJ-463
T69028
Synonym:
Target:
ZK824859 hydrochloride
T62961
Synonym:
Target:
PKSI-527
T35579
Synonym:
Target:
ZK824190 hydrochloride
T62731
Synonym:
Target:
Vitronectin
T80859
Synonym:
Target:
Plasminogen
T78018
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T6S1699 Shogaol [6]-Shogaol,6-Shogaol Lipoxygenase , Autophagy
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...

Natural Products

Shogaol
T6S1699
Synonym: [6]-Shogaol,6-Shogaol
Target: Lipoxygenase, Autophagy

Recombinant Proteins

Species：
Human (13)
Mouse (12)
Cynomolgus (2)
Rat (2)
Expression System：
HEK293 Cells (22)
E. coli (4)
Baculovirus Insect Cells (3)
Tag：
C-His (8)
C-His-Avi (7)
C-6xHis (4)
N-6xHis-SUMO (2)
C-10xHis (1)
C-hFc (1)
His, hFc (1)
N-10xHis (1)
N-10xHis, C-Myc (1)
N-10xHis-SUMO, C-Myc (1)
Cat No. Product Name Species Expression System
TMPY-00904 Urokinase/uPA Protein, Human, Recombinant (His) Human HEK293 Cells
Urokinase/uPA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is A0A024QZM9.
TMPY-04504 Urokinase/uPA Protein, Rat, Recombinant (His) Rat HEK293 Cells
Urokinase/uPA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.3 kDa and the accession number is A6KKR2.
TMPY-01257 UPAR/PLAUR Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
uPAR/PLAUR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is P35456-1.
TMPK-00782 PLAU/uPA Protein, Mouse, Recombinant (His & Avi) Mouse HEK293 Cells
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPY-02141 UPAR/PLAUR Protein, Human, Recombinant (His) Human HEK293 Cells
uPAR/PLAUR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q03405-1.
TMPY-01017 UPAR/PLAUR Protein, Mouse, Recombinant (His & hFc) Mouse HEK293 Cells
uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 58 kDa and the accession number is P35456-1.
TMPK-00539 PLAU/uPA Protein (active form), Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00783 PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-00274 PLAU/uPA Protein (active form), Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro...
TMPK-01225 MRC2 Protein, Human, Recombinant (His) Human HEK293 Cells
MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellu...
TMPY-01711 Serpin B2 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPH-01869 PAI-2 Protein, Human, Recombinant (His) Human HEK293 Cells
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. PAI-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis ...
TMPJ-00625 Serpin E1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. I...
TMPH-03397 UPAR/PLAUR Protein, Rat, Recombinant (His) Rat E. coli
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. uPAR/PLAUR Protein,...
TMPK-00216 UPAR/PLAUR Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-01175 UPAR/PLAUR Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00227 UPAR/PLAUR Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPH-01508 HABP2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fib...
TMPK-00228 UPAR/PLAUR Protein, Human, Recombinant (hFc) Human HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00215 UPAR/PLAUR isoform 1 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00226 UPAR/PLAUR Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPH-02922 SRPX2 Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus Insect Cells
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration...
TMPH-02923 SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO) Mouse E. coli
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration...
TMPY-01718 Serpin B12 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, infl...
TMPJ-01282 Serpin B12 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular f...
TMPJ-01320 BSSP-4 Protein, Human, Recombinant (His) Human HEK293 Cells
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial c...
TMPJ-01083 Serpin E2 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea...
TMPH-02834 PAI-1 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg...
TMPJ-00796 Serpin E2 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin E2 is a secreted protein that belongs to the serpin family. Serpin E2 is a serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Serpin E2 expression is weak or absent in all normal panc...
Urokinase/uPA Protein, Human, Recombinant (His)
TMPY-00904
Species: Human
Expression System: HEK293 Cells
Urokinase/uPA Protein, Rat, Recombinant (His)
TMPY-04504
Species: Rat
Expression System: HEK293 Cells
uPAR/PLAUR Protein, Mouse, Recombinant (His)
TMPY-01257
Species: Mouse
Expression System: HEK293 Cells
PLAU/uPA Protein, Mouse, Recombinant (His & Avi)
TMPK-00782
Species: Mouse
Expression System: HEK293 Cells
uPAR/PLAUR Protein, Human, Recombinant (His)
TMPY-02141
Species: Human
Expression System: HEK293 Cells
uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc)
TMPY-01017
Species: Mouse
Expression System: HEK293 Cells
PLAU/uPA Protein (active form), Cynomolgus, Recombinant (His)
TMPK-00539
Species: Cynomolgus
Expression System: HEK293 Cells
PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00783
Species: Mouse
Expression System: HEK293 Cells
PLAU/uPA Protein (active form), Human, Recombinant (His & Avi), Biotinylated
TMPK-00274
Species: Human
Expression System: HEK293 Cells
MRC2 Protein, Human, Recombinant (His)
TMPK-01225
Species: Human
Expression System: HEK293 Cells
Serpin B2 Protein, Human, Recombinant (GST)
TMPY-01711
Species: Human
Expression System: Baculovirus Insect Cells
PAI-2 Protein, Human, Recombinant (His)
TMPH-01869
Species: Human
Expression System: HEK293 Cells
Serpin E1 Protein, Mouse, Recombinant (His)
TMPJ-00625
Species: Mouse
Expression System: HEK293 Cells
uPAR/PLAUR Protein, Rat, Recombinant (His)
TMPH-03397
Species: Rat
Expression System: E. coli
uPAR/PLAUR Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00216
Species: Mouse
Expression System: HEK293 Cells
uPAR/PLAUR Protein, Cynomolgus, Recombinant (His)
TMPK-01175
Species: Cynomolgus
Expression System: HEK293 Cells
uPAR/PLAUR Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00227
Species: Human
Expression System: HEK293 Cells
HABP2 Protein, Human, Recombinant (His & SUMO)
TMPH-01508
Species: Human
Expression System: E. coli
uPAR/PLAUR Protein, Human, Recombinant (hFc)
TMPK-00228
Species: Human
Expression System: HEK293 Cells
uPAR/PLAUR isoform 1 Protein, Mouse, Recombinant (His & Avi)
TMPK-00215
Species: Mouse
Expression System: HEK293 Cells
uPAR/PLAUR Protein, Human, Recombinant (His & Avi)
TMPK-00226
Species: Human
Expression System: HEK293 Cells
SRPX2 Protein, Mouse, Recombinant (His & Myc)
TMPH-02922
Species: Mouse
Expression System: Baculovirus Insect Cells
SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO)
TMPH-02923
Species: Mouse
Expression System: E. coli
Serpin B12 Protein, Mouse, Recombinant (His)
TMPY-01718
Species: Mouse
Expression System: Baculovirus Insect Cells
Serpin B12 Protein, Human, Recombinant (His)
TMPJ-01282
Species: Human
Expression System: HEK293 Cells
BSSP-4 Protein, Human, Recombinant (His)
TMPJ-01320
Species: Human
Expression System: HEK293 Cells
Serpin E2 Protein, Mouse, Recombinant (His)
TMPJ-01083
Species: Mouse
Expression System: HEK293 Cells
PAI-1 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02834
Species: Mouse
Expression System: E. coli
Serpin E2 Protein, Human, Recombinant (His)
TMPJ-00796
Species: Human
Expression System: HEK293 Cells
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