telomerase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13115	Telomerase-IN-2	Telomerase inhibitor 2	Telomerase
	Telomerase-IN-2 (Telomerase inhibitor 2) shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 µM).		Telomerase
T12009	Telomerase-IN-1		Telomerase
	Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER overreaction (EOR), which then induces ERS, leading to apopto...		Telomerase
T41290	MST-312	Telomerase Inhibitor IX	Telomerase
	MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).		Telomerase
T13116	Telomerase-IN-3		Others
	Telomerase-IN-3 is an inhibitor of telomerase.		Others
T72789	Telomerase-IN-4		Apoptosis
	Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].		Apoptosis
T72790	Telomerase-IN-5		Apoptosis
	Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].		Apoptosis
T2380	BIBR 1532		Apoptosis , Telomerase
	BIBR 1532 is an effective, specific and non-competitive telomerase inhibitor (IC50: 100 nM, in a cell-free assay).		Apoptosis , Telomerase
T5575	Cycloastragenol	Cyclogalegenol,Astramembrangenin	Epigenetic Reader Domain , Telomerase
	Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape...		Epigenetic Reader Domain , Telomerase
T6133	Remodelin hydrobromide	Remodelin,Remodelin HBR	RAAS , Histone Acetyltransferase
	Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.		RAAS , Histone Acetyltransferase
T7409	360A		DNA/RNA Synthesis , Telomerase
	360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).		DNA/RNA Synthesis , Telomerase
T6S0923	Hypericin	Hypericine,Cyclosan	Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
	1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...
T13174	TMPyP4 tosylate	TMP 1363	DNA/RNA Synthesis , Telomerase
	TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.		DNA/RNA Synthesis , Telomerase
T10760	Ceramides Mixture		Telomerase
	Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ...		Telomerase
T8647	BCH001		DNA/RNA Synthesis
	BCH001 is a specific small-molecule inhibitor of PAPD5.		DNA/RNA Synthesis
T1267	Abacavir	Epzicom,Ziagen,Abacavir sulfate	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS.		Apoptosis , HIV Protease , Reverse Transcriptase
T6967	RHPS4	RHPS 4 methosulfate,NSC714187	Apoptosis , Telomerase
	RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.		Apoptosis , Telomerase
T6367	Abacavir sulfate	Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity		Apoptosis , HIV Protease , Reverse Transcriptase
T23819	Braco-19 trihydrochloride	BRAC-O19,BRACO19 hydrochloride,BRACO19 3HCl,BRACO 19,BRACO19 HCl	Telomerase
	Braco-19 trihydrochloride (BRACO19 3HCl) is an inhibitor of telomerase and prevents the capping and catalytic action of telomerase. Braco-19 trihydrochloride inhibits HAdV virus replication.		Telomerase
TP1291	Epithalon TFA (307297-39-8 free base)	Epithalon TFA	Others
	Epithalon TFA (307297-39-8 free base) (Epithalon TFA) is an anti-aging agent and telomerase activator.		Others
T6746	6-Thio-2'-Deoxyguanosine	6-Thio-dG,β-TGdR	Others , DNA/RNA Synthesis
	6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.		Others , DNA/RNA Synthesis