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MST-312

Catalog No. T41290   CAS 368449-04-1
Synonyms: Telomerase Inhibitor IX

MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
MST-312 Chemical Structure
MST-312, CAS 368449-04-1
Pack Size Availability Price/USD Quantity
2 mg In stock $ 34.00
5 mg In stock $ 55.00
10 mg In stock $ 97.00
25 mg In stock $ 197.00
50 mg In stock $ 367.00
100 mg In stock $ 546.00
1 mL * 10 mM (in DMSO) In stock $ 61.00
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Purity: 99.17%
Purity: 98.87%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).
In vitro In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1].
Synonyms Telomerase Inhibitor IX
Molecular Weight 380.35
Formula C20H16N2O6
CAS No. 368449-04-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Insoluble

DMSO: 70 mg/mL (184.04 mM), ultrasonic and warming and heat to 60°C

TargetMolReferences and Literature

1. Ameri Z, et al. Telomerase inhibitor MST-312 induces apoptosis of multiple myeloma cells and down-regulation of anti-apoptotic, proliferative and inflammatory genes. Life Sci. 2019;228:66-71.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Bioactive Compound Library Inhibitor Library DNA Damage & Repair Compound Library Anti-Cancer Compound Library Bioactive Compounds Library Max

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Keywords

MST-312 368449-04-1 DNA Damage/DNA Repair Telomerase EGCG epigallocatechin gallate MST312 Inhibitor multiple tea MST 312 derivative cancer inhibit Telomerase Inhibitor IX myeloma inhibitor

 

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