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MST-312

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Purity:99.17%

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COA HPLC LCMS HNMR

MST-312

Catalog No. T41290Cas No. 368449-04-1

MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).

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Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$44	In Stock
10 mg	$73	In Stock
25 mg	$147	In Stock
50 mg	Inquiry	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Product Introduction

Bioactivity

Description	MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM).
In vitro	In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1].
Alias	Telomerase Inhibitor IX

Chemical Properties

Molecular Weight	380.35
Formula	C20H16N2O6
Cas No.	368449-04-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Insoluble

DMSO: 50 mg/mL (131.46 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6292 mL	13.1458 mL	26.2916 mL	131.4579 mL
5 mM	0.5258 mL	2.6292 mL	5.2583 mL	26.2916 mL
10 mM	0.2629 mL	1.3146 mL	2.6292 mL	13.1458 mL
20 mM	0.1315 mL	0.6573 mL	1.3146 mL	6.5729 mL
50 mM	0.0526 mL	0.2629 mL	0.5258 mL	2.6292 mL
100 mM	0.0263 mL	0.1315 mL	0.2629 mL	1.3146 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc