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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37577 | Glycogen Phosphorylase Inhibitor | ||
Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibit... | |||
TP1056 | Phosphorylase Kinase β-Subunit Fragment (420-436) | Phosphorylase Kinase β-Subunit(420-436),Phosphorylase Kinase β-Subunit Fragment 420-436 | |
Phosphorylase Kinase β-Subunit Fragment (420-436) is a peptide fragment (430-436) derived from the β-Subunit of phosphorylase kinase. Phosphorylase kinase, a serine/threonine-specific protein kinase, plays a crucial role... | |||
T76100 | Maltose phosphorylase | ||
Maltose phosphorylase, a dimerase belonging to family 65 of the glycoside hydrolases [1], catalyzes the conversion of maltose and inorganic phosphate into β-D-glucose-1-phosphate and glucose. | |||
T76103 | Sucrose phosphorylase | ||
Sucrose phosphorylase, a bacterial transglucosidase, catalyzes the conversion of sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose. This enzyme can also hydrolyze glucosylated sucrose into α-D-glucose or ... | |||
T76096 | Purine nucleoside phosphorylase | ||
Purine Nucleoside Phosphorylase, an essential enzyme in purine metabolism, plays a critical role in the purine salvage pathway. Its deficiency impairs T cell function. With inorganic orthophosphate as a co-substrate, thi... | |||
T8155 | Maltoheptaose | Phospholipase | |
Maltoheptaose is an activator of phosphorylase B for the preparation of heptulose-2-phosphate. | |||
T75401 | D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP) | ||
D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP), belonging to the CAZy glycoside hydrolase family GH112, plays a pivotal role in biochemical research. This enzyme catalyzes the phosphorolysis of lact... | |||
T9727 | 2'-Fluoro-2'-Deoxyadenosine | Nucleoside Antimetabolite/Analog | |
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors ex... | |||
T12399 | Peldesine | BCX 34 | Nucleoside Antimetabolite/Analog , HIV Protease |
Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in resear... | |||
T14141 | AGI-24512 | Others , Methionine Adenosyltransferase (MAT) | |
AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro. | |||
T75398 | UDP-sugar pyrophosphorylase (BlUSP) | ||
UDP-sugar pyrophosphorylase (BlUSP) is an enzyme that activates glucose-1-phosphate (Glc-1-P) to UDP-glucose (UDP-Glc) and catalyzes the reversible transfer of the uridyl group from UTP to sugar-1-phosphate, resulting in... | |||
T8493 | Ingliforib | GPi 296,CP 368296 | Phosphorylase |
Ingliforib (CP 368296) is a novel glycogen phosphorylase inhibitor,has antihyperglycemic and cardioprotective properties. | |||
T0745 | Disodium monofluorophosphate | Sodium Monofluorophosphate,NSC248 | Phosphatase , PKM , Phosphorylase |
Disodium monofluorophosphate (NSC248) is a competitive inhibitor of pyruvate kinase and alkaline phosphatase, which also irreversibly inhibits phosphorylase phosphatase. | |||
T7782 | 3'-Deoxyguanosine | Others | |
3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors. | |||
T15337 | Forodesine | BCX-1777,Immucillin-H | Others |
Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could i... | |||
T3S1850 | Bayogenin | Others | |
Bayogenin is an alfalfa saponin, Bayogenin shows moderate potency of glycogen phosphorylase inhibition. | |||
TQ0008 | MT-DADMe-ImmA | Methylthio-DADMe-Immucillin A,MTDIA | Others |
MT-DADMe-ImmA (MTDIA) is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM). | |||
T1709 | 2'-Deoxyinosine | Guanine deoxyriboside,Deoxyinosine | Others , Endogenous Metabolite |
2'-Deoxyinosine (Guanine deoxyriboside) inhibits the growth of human colon-carcinoma cell lines and is associated with purine nucleoside phosphorylase (PNP) deficiency. | |||
T10421 | AVE5688 | Phosphorylase | |
AVE5688 is an inhibitor of glycogen phosphorylase (GP, IC50s: 430 nM and 915 nM; Kds: 170 nM and 530 nM for rmGPb and rmGPa). It can be used for the research of type 2 diabetes. | |||
T6680 | Staurosporine | Antibiotic AM-2282,AM-2282,CGP 41251 | Apoptosis , PKA , Antibacterial , Antibiotic , Src , PKC , Antifungal |
Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces... |