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Search Result

Search Results for " pth "

Targets

Thyroid hormone receptor(THR)

39

Compounds

2

Natural Products

12

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9691L (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate Thyroid hormone receptor(THR)
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membrane.
T81352 pTH (2-38) (human)
PTH (2-38) (human) plays a role in bone anabolism and can elevate serum levels of INS-PTH (complete N-terminal specific PTH) [1].
T76660 pTH (1-37) (human)
pTH (1-37) (human), a fragment of parathyroid hormone (PTH), promotes cAMP formation and enhances alkaline phosphatase activity. Additionally, it fosters growth, elevates bone calcium content, and augments bone mineral d...
T76657 Human PTH-(1-31)
Human PTH-(1-31), the 1-31 fragment of human parathyroid hormone, stimulates cAMP release and mildly activates 25-hydroxyvitamin D-1α-hydroxylase. Unlike its full-length counterpart, it promotes bone formation without tr...
T76657L Human PTH-(1-31) amide
Human PTH-(1-31) amide, an analog of PTH, effectively stimulates phosphatidylcholine hydrolysis and promotes the release of adenylyl cyclase [1].
T81350 pTH-Related Protein (1-37) (human, mouse, rat)
PTH-Related Protein (1-37) (human, mouse, rat) is a peptide analog of parathyroid-hormone-related protein (pTHrP), which plays a role in the physiological regulation of bone formation [1].
T76663 pTH-Related Protein (1-40) (human, mouse, rat)
pTH-Related Protein (1-40) (human, mouse, rat) enhances calcium absorption in rat intestinal cells by activating the PTHR1 receptor and the PKCα/β signaling pathways. This compound also increases the expression of the pa...
T13128 Teriparatide Human parathyroid hormone-(1-34),hPTH (1-34),PTH 1-34 Others
Teriparatide is an agonist of PHT(IC50 of 2 nM in HEK293 cells).
T76636 (Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
'(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat), a peptide, functions as a ligand for parathyroid hormone (PTH) receptors [1].'
T81351 pTH-Related Protein (1-34) amide (human, mouse, rat) Human PTHrP-(1-34)NH2
Human PTHrP-(1-34)NH2, also known as PTH-Related Protein (1-34) amide for human, mouse, and rat, is the N-terminal fragment of PTHrP. This peptide induces hypercalcemia and is utilized in the study of humoral hypercalcem...
T81349 pTH-Related Protein (7-34) amide (human, mouse, rat)
PTH-Related Protein (7-34) amide (human, mouse, rat) serves as a potent antagonist of parathyroid hormone (PTH) [1].
T76586 (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat)
(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent antagonist of the PTH-1R [1] [2].
T8344 CPTH2 Apoptosis , Histone Acetyltransferase
CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.
TP1602 [pThr3]-CDK5 Substrate
[pThr3]-CDK5 Substrate is an effective Phospho-Thr3CDK5 Substrate.[pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM[1].
TP1660 [pThr3]-CDK5 Substrate (TFA)
[pThr3]-CDK5 Substrate TFA is an effective Phospho-Thr3CDK5 Substrate. [pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM.
T76031 [pThr3]-CDK5 Substrate TFA
[pThr3]-CDK5 Substrate TFA, a potent Phospho-Thr3CDK5 Substrate, originates from the histone H1 peptide sequence that binds to CDK5's active site. This substrate undergoes phosphorylation by CDK5, demonstrating a K_m val...
T77990 Human PTHrP-(1-36)
Human PTHrP-(1-36) is a secreted form of parathyroid hormone-related protein that exhibits anticalciuric effects and promotes beta cell function and proliferation. It is utilized in research pertaining to humoral hyperca...
T25397 Ethyl dicapthon AI310615,AI3 10615,AI3-10615
Ethyl dicapthon is used as an insecticide.
T19830 Dicapthon AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124
Dicapthon is an insecticide. Dicapthon increases the occurrence of abnormal cell frequency, decreases the mitotic index, and decreases the nuclear division index.
T22693 CPTH2 (hydrochloride) (357649-93-5 free base) CPTH2 (hydrochloride) Others
CPTH2 is an inhibitor of the HAT activity of Gcn5.
TP1236 Etelcalcetide hydrochloride AMG 416 hydrochloride,KAI-4169 hydrochloride CaSR
Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide that acts as an allosteric modulator of the calcium-sensing receptor (CaSR), effectively lowering parathyroid hormone (PTH) levels in patients wi...
TP1906L1 DPC AJ1951 acetate Thyroid hormone receptor(THR)
DPC-AJ1951 acetate, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 acetate in ex vivo and in vivo a...
T21535 Parathyroid Hormone (1-34), bovine Thyroid hormone receptor(THR)
Parathyroid Hormone (1-34), bovine is a parathyroid hormone (PTH) receptor agonist that is part of the parathyroid hormone family. Parathyroid Hormone (1-34), bovine is used to study osteoporosis and hypoparathyroidism.
T29067L Upacicalcet HCl Upacicalcet HCl(1333218-50-0 Free base) CaSR
Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors in parathyroid cell membranes, thereby lowering PTH levels ...
T16015 Maxacalcitol 22-Oxacalcitriol Others
Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo.
T29067 Upacicalcet PLS-240,SK-1403,AJT-240 Calcium Channel
Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-s...
T39444 Upacicalcet sodium
Upacicalcet (sodium) is an intravenous calcimimetic agent that acts directly on parathyroid cell membrane calcium-sensing receptors to suppress excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH le...
T75942 DPC-AJ1951 TFA
DPC-AJ1951 TFA, a 14-amino acid peptide, functions as a potent agonist for the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). It has been characterized for its activity through ex vivo and in vivo bone res...
TP1964 Parathyroid hormone (1-34) (rat)
Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.
T36767 Parathyroid Hormone (1-13) (trifluoroacetate salt)
Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34) . In vivo, PTH (1-13) (0.003-1 μmol/kg) increases mean arterial pressure (MAP) in anesthetized rats.
TP1906 DPC-AJ1951 DPC AJ1951
Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM).
TP1688 TIP 39, Tuberoinfundibular Neuropeptide
This is a tuberoinfundibular neuropeptide and parathyroid hormone 2(PTH 2)-receptor agonist from hypothalmus. Synthetic TIP39 activates human and rat PTH2 receptors.
T36919 1α-Hydroxy-3-epi-vitamin D3 1α-Hydroxy-3-epi-vitamin D3
1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].
T61232 (Rac)-Upacicalcet
(Rac)-Upacicalcet is a racemate of Upacicalcet, which serves as an intravenous calcimimetic agent. Upacicalcet acts by directly targeting calcium-sensing receptors on parathyroid cell membranes, effectively suppressing t...
T73692 Parathyroid hormone
Parathyroid hormone (PTH), an 84-amino acid circulating hormone synthesized in the parathyroid glands, primarily regulates bone and kidney functions to maintain extracellular calcium levels within normal ranges. It is al...
T37409 DPC-AJ1951 (trifluoroacetate salt) DPC-AJ1951 (trifluoroacetate salt)
DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR). It induces cAMP production in SAOS-2 and UMR106 cells that endogen...
T75867 Parathyroid Hormone (1-34), bovine TFA
Parathyroid Hormone (1-34), bovine TFA, a potent agonist of the parathyroid hormone (PTH) receptor, elevates calcium and inorganic phosphate levels in vivo. This compound is employed in osteoporosis research [1].
TP2283 Parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis] Others
parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid...
T35500 3-epi-25-hydroxy Vitamin D3 3-epi-25-hydroxy Vitamin D3
3-epi-25-hydroxy Vitamin D3is the C-3 epimer of 25-hydroxy vitamin D3.1Dietary administration of 3-epi-25-hydroxy vitamin D3(0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, we...

Compounds

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
T9691L
Synonym:
Target: Thyroid hormone receptor(THR)
pTH (2-38) (human)
T81352
Synonym:
Target:
pTH (1-37) (human)
T76660
Synonym:
Target:
Human PTH-(1-31)
T76657
Synonym:
Target:
Human PTH-(1-31) amide
T76657L
Synonym:
Target:
pTH-Related Protein (1-37) (human, mouse, rat)
T81350
Synonym:
Target:
pTH-Related Protein (1-40) (human, mouse, rat)
T76663
Synonym:
Target:
Teriparatide
T13128
Synonym: Human parathyroid hormone-(1-34),hPTH (1-34),PTH 1-34
Target: Others
(Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat)
T76636
Synonym:
Target:
pTH-Related Protein (1-34) amide (human, mouse, rat)
T81351
Synonym: Human PTHrP-(1-34)NH2
Target:
pTH-Related Protein (7-34) amide (human, mouse, rat)
T81349
Synonym:
Target:
(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat)
T76586
Synonym:
Target:
CPTH2
T8344
Synonym:
Target: Apoptosis, Histone Acetyltransferase
[pThr3]-CDK5 Substrate
TP1602
Synonym:
Target:
[pThr3]-CDK5 Substrate (TFA)
TP1660
Synonym:
Target:
[pThr3]-CDK5 Substrate TFA
T76031
Synonym:
Target:
Human PTHrP-(1-36)
T77990
Synonym:
Target:
Ethyl dicapthon
T25397
Synonym: AI310615,AI3 10615,AI3-10615
Target:
Dicapthon
T19830
Synonym: AC4124,AC 4124,Captex,ENT-17035,ENT 17035,AC-4124
Target:
CPTH2 (hydrochloride) (357649-93-5 free base)
T22693
Synonym: CPTH2 (hydrochloride)
Target: Others
Etelcalcetide hydrochloride
TP1236
Synonym: AMG 416 hydrochloride,KAI-4169 hydrochloride
Target: CaSR
DPC AJ1951 acetate
TP1906L1
Synonym:
Target: Thyroid hormone receptor(THR)
Parathyroid Hormone (1-34), bovine
T21535
Synonym:
Target: Thyroid hormone receptor(THR)
Upacicalcet HCl
T29067L
Synonym: Upacicalcet HCl(1333218-50-0 Free base)
Target: CaSR
Maxacalcitol
T16015
Synonym: 22-Oxacalcitriol
Target: Others
Upacicalcet
T29067
Synonym: PLS-240,SK-1403,AJT-240
Target: Calcium Channel
Upacicalcet sodium
T39444
Synonym:
Target:
DPC-AJ1951 TFA
T75942
Synonym:
Target:
Parathyroid hormone (1-34) (rat)
TP1964
Synonym:
Target:
Parathyroid Hormone (1-13) (trifluoroacetate salt)
T36767
Synonym:
Target:
DPC-AJ1951
TP1906
Synonym: DPC AJ1951
Target:
TIP 39, Tuberoinfundibular Neuropeptide
TP1688
Synonym:
Target:
1α-Hydroxy-3-epi-vitamin D3
T36919
Synonym: 1α-Hydroxy-3-epi-vitamin D3
Target:
(Rac)-Upacicalcet
T61232
Synonym:
Target:
Parathyroid hormone
T73692
Synonym:
Target:
DPC-AJ1951 (trifluoroacetate salt)
T37409
Synonym: DPC-AJ1951 (trifluoroacetate salt)
Target:
Parathyroid Hormone (1-34), bovine TFA
T75867
Synonym:
Target:
parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]
TP2283
Synonym:
Target: Others
3-epi-25-hydroxy Vitamin D3
T35500
Synonym: 3-epi-25-hydroxy Vitamin D3
Target:
Cat No. Product Name Synonyms Targets
T6430 Calcifediol U 32070E,25-hydroxy Vitamin D3,RO 8-8892 Endogenous Metabolite
Calcifediol (U 32070E)(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.
T16442 PCO371 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl- Thyroid hormone receptor(THR)
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...

Natural Products

Calcifediol
T6430
Synonym: U 32070E,25-hydroxy Vitamin D3,RO 8-8892
Target: Endogenous Metabolite
PCO371
T16442
Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-
Target: Thyroid hormone receptor(THR)

Recombinant Proteins

Species：
Human (8)
Rat (3)
Cynomolgus (1)
Expression System：
E. coli (8)
HEK293 Cells (3)
P. pastoris (Yeast) (1)
Tag：
N-6xHis (3)
N-10xHis, C-Myc (2)
Tag Free (2)
GST (1)
His (1)
N-8xHis (1)
N-His (1)
hFc (1)
Cat No. Product Name Species Expression System
TMPY-03191 PTH Protein, Human, Recombinant (hFc) Human HEK293 Cells
PTH Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.9 kDa and the accession number is P01270.
TMPJ-00740 PTH Protein, Human, Recombinant Human E. coli
Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells...
TMPJ-00741 PTH Protein, Human, Recombinant (His) Human HEK293 Cells
Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This ho...
TMPY-02764 PTH Protein, Human, Recombinant (aa 32-65, GST) Human E. coli
PTH Protein, Human, Recombinant (aa 32-65, GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 31 kDa and the accession number is P01270.
TMPH-03348 PTH Protein, Rat, Recombinant (His & Myc) Rat E. coli
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. PTH Protein, Rat, Recomb...
TMPY-03572 PTRH2 Protein, Human, Recombinant (His) Human E. coli
PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs whic...
TMPH-02434 PTH Protein, Cynomolgus, Recombinant (His & Myc) Cynomolgus E. coli
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. PTH Protein, Cynomolgus,...
TMPY-02236 PTH1R Protein, Human, Recombinant (His) Human HEK293 Cells
Parathyroid hormone / parathyroid hormone-related peptide receptor, also known as PTH / PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor, PTH1R and PTHR, is a multi-pass membrane pr...
TMPH-01848 PTHLH Protein, Human, Recombinant (His) Human E. coli
PTHLH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.7 kDa and the accession number is P12272.
TMPH-03294 FGF-23 Protein, Rat, Recombinant (His) Rat P. pastoris (Yeast)
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Ac...
TMPH-03293 FGF-23 Protein, Rat, Recombinant (E. coli, His) Rat E. coli
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Ac...
TMPJ-00464 APE Protein, Human, Recombinant Human E. coli
Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete re...
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