Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Calcifediol (U 32070E)(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 313.00 | |
50 mg | In stock | $ 513.00 | |
100 mg | In stock | $ 747.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 118.00 |
Description | Calcifediol (U 32070E)(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA. |
Targets&IC50 | vitamin D3:3.9 μM(ki), PTH:2 nM(ED50) |
In vitro | Calcifediol in either liposomes or ethanolic solution has no effect on the release of the proinflammatory cytokine KC from Pseudomonas-infected murine epithelial cells. Treatment of infected, human bronchial 16-HBE cells with Calcifediol liposomes shows a significant reduction result in bacterial survival[1]. |
Synonyms | U 32070E, 25-hydroxy Vitamin D3, RO 8-8892 |
Molecular Weight | 400.64 |
Formula | C27H44O2 |
CAS No. | 19356-17-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 74 mg/mL (184.7 mM)
Ethanol: 16 mg/mL (39.9 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Calcifediol 19356-17-3 Metabolism Endogenous Metabolite U 32070E 25-hydroxy Vitamin D3 Vitamin D receptor RO 8-8892 VD/VDR Vitamin D Inhibitor inhibit inhibitor