Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CPTH2 is an inhibitor of the HAT activity of Gcn5.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 35 days | $ 243.00 | |
10 mg | 35 days | $ 320.00 |
Description | CPTH2 is an inhibitor of the HAT activity of Gcn5. |
In vitro | In vitro: The previous study identified a novel molecule named CPTH2, which was selected based on its inhibitory effect on the growth of a gcn5Delta strain. This study indicated a specific chemical-genetic interaction between CPTH2 and HAT Gcn5p, suggesting that CPTH2 could inhibit the dependent functional network of Gcn5p. In addition, CPTH2 was found to be able to inhibit an in-vitro HAT reaction, which could be reversed by increasing the concentration of histone H3 [1]. |
In vivo | In vivo: CPTH2 could decrease the acetylation of bulk histone H3 at the specific H3-AcK14 site [1]. |
Synonyms | CPTH2 (hydrochloride) |
Molecular Weight | 328.26 |
Formula | C14H15Cl2N3S |
CAS No. | 2108899-91-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 16mg/ml
Ethanol: ≤5mg/mL
You can also refer to dose conversion for different animals. More
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