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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60108 | PDGFR Tyrosine Kinase Inhibitor III | PDGF Receptor Tyrosine Kinase Inhibitor III | PDGFR |
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGF... | |||
T14137 | AG 1295 | PDGFR | |
AG 1295, a selective inhibitor of platelet-derived growth factor receptor (PDGFR) tyrosine-kinase, effectively halts PDGFR autophosphorylation without impacting the autophosphorylation of the EGF receptor[1][2][3][4]. | |||
T15031 | CYM50260 | Others , LPL Receptor | |
CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R. | |||
T6711 | Tyrphostin AG1296 | Tyrphostin AG 1296,AG 1296 | Apoptosis , FGFR , FLT , PDGFR , c-Kit |
Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. | |||
T60110 | KN1022 | PDGFR | |
KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM. | |||
T6996 | SU 5402 | SU5402 | VEGFR , FGFR , PDGFR |
SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively. | |||
T4205 | AG-494 | Tyrphostin AG-494,AG 494,Tyrphostin B48 | EGFR , CDK |
AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase. | |||
T23127 | PD-161570 | PD 161570 | EGFR , FGFR , PDGFR , Src |
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a... | |||
T21784 | AG-370 | ||
AG 370, an indole tyrphostin, functions as a powerful inhibitor of PDGF-induced mitogenesis, demonstrating an IC50 of 20 μM. Additionally, it exhibits weak inhibition capabilities towards the EGF receptor. | |||
T67442 | CGP-53716 | ||
The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase i... | |||
T37079 | VEGFR2 Kinase Inhibitor II | ||
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms... |