nmdar — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5522	NMDAR antagonist 1		Others , iGluR
	NMDAR antagonist 1 is an orally active, NR2B-selective NMDAR antagonist.		Others , iGluR
T72662	NMDAR/TRPM4-IN-2		ERK , TRP/TRPV Channel , NMDAR , iGluR
	NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprot...		ERK , TRP/TRPV Channel , NMDAR , iGluR
T61451	NMDAR/HDAC-IN-1
	NMDAR/HDAC-IN-1 (Compound 9d) is a potent dual inhibitor of N-methyl-D-aspartate receptors (NMDARs) and histone deacetylases (HDACs). It exhibits a high affinity (Ki = 0.59 μM) for NMDARs, while demonstrating significant...
T62126	(Rac)-NMDAR antagonist 1
	(Rac)-NMDAR antagonist 1 is a racemate of NMDAR antagonist 1. NMDAR antagonist 1 is a potent, orally active, NR2B-selective NMDAR antagonist.
T74854	GluN2B-NMDAR antagonist-1
	GluN2B-NMDAR Antagonist-1, an orally active compound, functions as a GluN2B-NMDAR antagonist with neuroprotective properties. It is applicable in the research of ischemic injury [1].
T7870	TCN 201	TCN-201	NMDAR , iGluR
	TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.		NMDAR , iGluR
T2556	Nandrolone decanoate	19-Nortestosterone decanoate	Others , HIV Protease
	Nandrolone decanoate (19-Nortestosterone decanoate) is the decanoate salt form of nandrolone, an anabolic steroid analog of testosterone with androgenic, anabolic, and erythropoietin stimulating effects. Nandrolone enter...		Others , HIV Protease
T6504	Flupirtine maleate	Katadolon maleate	Potassium Channel , NMDAR , iGluR
	Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener.		Potassium Channel , NMDAR , iGluR
T0556	6-Methoxy-2-naphthoic acid	Naproxen impurity O,6-Methoxy-2-naphthalenecarboxylic acid	NMDAR , iGluR
	6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.		NMDAR , iGluR
T8450	TCN 213	TCN213	NMDAR
	TCN 213 is an antagonist of NMDA receptor that has a selective for NR1/NR2A over NR1/NR2B		NMDAR
T6975	Sarcosine	Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine	Others , GlyT , Endogenous Metabolite
	Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.		Others , GlyT , Endogenous Metabolite
T13112L1	Tat-NR2B9c acetate	Tat-NR2B9c acetate (500992-11-0 Free base),NA-1 acetate	Others
	Tat-NR2B9c acetate (NA-1 acetate) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively. Tat-NR2B9c acetate disrupts the PSD-...		Others
T8394	D-Serine	(R)-Serine	Endogenous Metabolite , NMDAR , iGluR
	D-Serine ((R)-Serine) is an endogenous amino acid,is a potent co-agonist at the NMDA glutamate receptor.		Endogenous Metabolite , NMDAR , iGluR
T7355	IC87201		Others , iGluR
	IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain.		Others , iGluR
T10781	CGP 78608 hydrochloride	PAMQX	NMDAR , iGluR
	CGP 78608 hydrochloride is a specific antagonist at the glycine binding site of the NMDA receptor (IC50 = 6 nM). CGP 78608 hydrochloride exhibits anticonvulsant activity. CGP 78608 hydrochloride potentiates GluN1/GluN3A-...		NMDAR , iGluR
T4171	PEAQX	NVP-AAM077	NMDAR , iGluR
	PEAQX (NVP-AAM077)(NVP-AAM 077) is an effective and orally available NMDA antagonist. It can inhibit human NMDA receptors for 1A/2A(IC50: 270 nM), rather than 1A/2B(29, 600 nM).		NMDAR , iGluR
T22798	Gavestinel	GV 150526,Gavestinel sodium salt	NMDAR , iGluR
	Gavestinel (GV 150526) is a non-competitive NMDA receptor antagonist that is potent, selective and orally active.Gavestinel binds to the glycine site of the NMDA receptor with a binding affinity (pKi value) of 8.5.Gavest...		NMDAR , iGluR
TQ0233	Traxoprodil	CP101606	NMDAR , iGluR
	Traxoprodil (CP101606) is a selective NMDA antagonist and protects hippocampal neurons (IC50: 10 nM).		NMDAR , iGluR
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
T3320	Dizocilpine Maleate	(+)-Mk-801 Hydrogen Maleate,MK 801,Dizocilpine hydrogen maleate,(+)-MK 801 maleate,(+)-MK 801 (Maleate)	NMDAR , iGluR
	Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of ne...		NMDAR , iGluR