mk-5 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22987	MK 212 hydrochloride		5-HT Receptor
	MK 212 hydrochloride is a 5-HT2C receptor agonist		5-HT Receptor
T68103L	Mk-6186 HCl	Mk-6186 HCl（1034474-19-5 Free base)	HIV Protease , Reverse Transcriptase
	MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.		HIV Protease , Reverse Transcriptase
T16087	Quiflapon	MK-591	Apoptosis , FLAP
	Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotr...		Apoptosis , FLAP
T0488	Finasteride	MK-906	Reductase
	Finasteride (MK-906) is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.		Reductase
T1512	Rizatriptan benzoate	MK-462 Benzoate	5-HT Receptor
	Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches.		5-HT Receptor
T1509	Cyclobenzaprine hydrochloride	Cyclobenzaprine HCl,MK130 hydrochloride	5-HT Receptor
	Cyclobenzaprine hydrochloride (MK130 hydrochloride) , a centrally acting muscle relaxant with antidepressant activity, leads to a reduction in muscle spasms.		5-HT Receptor
T6893	MK-886	MK886,L 663536	Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
	MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP). It is also a moderately potent PPARα antagonist.		Apoptosis , Leukotriene Receptor , COX , PPAR , FLAP
T1077	Fluvoxamine maleate	MK-264,DU-23000 (maleate)	5-HT Receptor , Serotonin Transporter
	Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.		5-HT Receptor , Serotonin Transporter
T9034	MK2-IN-3	MK2 Inhibitor III	MAPK
	MK2-IN-3 (MK2 Inhibitor III) is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis		MAPK
T71976	Fmoc-5-aminopentanoic acid
	Fmoc-5-aminopentanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected unde...
T11194	Enalaprilat D5	MK-422 D5	Others
	Enalaprilat D5 is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.		Others
T11192	Enalapril D5 maleate	MK-421 D5 maleate	Others
	Enalapril D5 maleate is deuterium labeled Enalapril, which is an angiotensin converting enzyme (ACE) inhibitor.		Others
T11193	Enalaprilat-d5 sodium	MK-422 D5 Sodium Salt,Enalaprilat D5 Sodium Salt	Others
	Enalaprilat D5 Sodium Salt is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor.		Others
T2625	MK-0752		Beta Amyloid , Gamma-secretase
	MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).		Beta Amyloid , Gamma-secretase
T13555	Ascr#2	Ascaroside C6	Others
	Ascr#2 (asc-C6-MK) is a glycoside analogue in Cryptococcus hidradii that promotes dauer formation.Ascr#2 mixtures with ascr#3 at low concentrations act as a male elicitor and can be used to detect population density.Ascr...		Others
T62544	MK-8153
	MK-8153 is a selective, potent, orally active inhibitor of extrarenal medullary potassium channels (ROMK), acting on ROMK EP (IC50: 5 μM) and hERG EP (IC50: 34 μM).MK-8153 can be used as a diuretic.
T79684	5-HT6R antagonist 1		5-HT Receptor
	Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability but also reverses MK-801-induced memory impairments in rats, ...		5-HT Receptor
T21558	MK-3207
	MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep...
T38844	MK-8245 Trifluoroacetate
	MK-8245 trifluoroacetate is a phenoxy piperidine isoxazole derivative functioning as a potent, liver-targeting stearoyl-CoA desaturase (SCD) inhibitor, demonstrating significant anti-diabetic and anti-dyslipidemic effect...