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Fluvoxamine maleate

Catalog No. T1077 CAS 61718-82-9

Synonyms: DU-23000 (maleate), MK-264

Fluvoxamine maleate is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.

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Fluvoxamine maleate, CAS 61718-82-9

Pack Size	Availability	Price/USD
10 mg	In stock	49.00
25 mg	In stock	69.00
50 mg	In stock	82.00
100 mg	In stock	124.00
200 mg	In stock	198.00

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Purity 99.92%

HNMR HPLC COA

Purity 99.97%

HNMR HPLC COA

Datasheet SDS

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Fluvoxamine maleate is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.
Targets&IC50	5-HT
In vitro	Fluvoxamine increases [5-HT]ex levels in rat the prefrontal cortex and thalamus, and also increases [DA]ex levels in the striatum. [1] Fluvoxamine maleate ameliorates tactile allodynia via spinal 5-HT2A/2C receptors, by acting on the receptors or 5-HT neurons. [2]

Synonyms	DU-23000 (maleate) , MK-264
Purity	99.92%
Molecular Weight	434.41
Formula	C19H25F3N2O6
CAS No.	61718-82-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

DMSO: 200.3 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature

1. Denys D, et al. Psychopharmacology (Berl),2004, 176(2), 195-203. 2. Honda M, et al. Neuropharmacology,2006, 51(4), 866-872. 3. Ohashi S, et al. Brain Res,2002, 949(1-2), 131-138. 4. Kojima T, et al. Brain Res,2003, 959(1), 165-168. 5. Velasco A, et al. Gen Pharmacol,1997, 28(4), 509-512.

Related compound libraries

This product is contained In the following compound libraries：

Approved Drug Library Bioactive Compound Library Inhibitor Library Anti-Cancer Compound Library Neuronal Signaling Compound Library Serotonin Receptor-Targeted Compound Library FDA-Approved Drug Library GPCR Compound Library Fluorochemical Library CNS-Penetrant Compound Library Drug Repurposing Compound Library Neurotransmitter Receptor Compound Library Drug-induced Liver Injury (DILI) Compound Library NMPA-Approved Drug Library FDA-Approved & Pharmacopeia Drug Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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