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Search Results for " mic-10 "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T79088	Chlamydia pneumoniae-IN-1
	Chlamydia pneumoniae-IN-1 (compound 55), a benzimidazole derivative, exhibits potent antibacterial activity, inhibiting 99% of C. pneumoniae growth at a concentration of 10 μM and maintaining 95% viability of the host ce...
T38240	2,6-Dichlorodiphenylamine		Antibacterial
	2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1...		Antibacterial
T40304	Antitubercular agent-10
	Antitubercular agent-10 shows potent antitubercular activity with a MIC value of 30 nM.
T80294	GLK-19
	GLK-19, an antimicrobial peptide, exhibits activity against E. coli with a minimum inhibitory concentration (MIC) of 10 μM [1].
T23954	Dactylfungin A
	Dactylfungins A is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.
T23955	Dactylfungin B
	Dactylfungins B is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.
T80377	Xenopsin precursor fragment		Parasite
	Xenopsin precursor fragment, an antimicrobial peptide, exhibits both antibacterial/antifungal activity at concentrations ranging from 10 to 500 μg/mL and anti-protozoal activity with a minimum inhibitory concentration (M...		Parasite
T80407	Peptide 5g
	Peptide 5g, an antimicrobial peptide, inhibits E. coli, S. aureus, and C. albicans, exhibiting minimum inhibitory concentration (MIC) values of 30, 10, and 12.5 μg/mL, respectively [1].
T71449	Capreomycin free base
	Capreomycin is a polypeptide antibiotic originally isolated from S. capreolus. It is active against M. tuberculosis (MIC = 10 µg/ml). Capreomycin binds to both the 30S and 50S ribosomal subunits, inhibiting protein synth...
T63512	LpxC-IN-10
	LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.
T83065	Antifungal agent 85
	Compound 24f, an antifungal agent also known as 'Antifungal agent 85,' demonstrates potent antibacterial properties, exhibiting minimum inhibitory concentration (MIC) values ranging from 2.5 to 10 μM against diverse Gram...
T80368	Im5
	Im5, an antimicrobial peptide, exhibits antibacterial activity, with minimum inhibitory concentrations (MIC) of 10 μM for E. coli, 2.5-5 μM for S. aureus, and 0.5-1 μM for B. subtilis, as well as hemolytic activity with ...
T79440	DprE1-IN-5
	DprE1-IN-5 (Compound 10), a potent DprE1 inhibitor, exhibits anti-TB activity with an MIC of 4 μM against the Mtb H37Rv strain and demonstrates antimycobacterial efficacy against drug-resistant strains. Additionally, it ...
T38289	Leucomycin A13	Leucomycin A13
	Leucomycin A13 is a macrolide antibiotic and a component of the leucomycin complex originally isolated from S. kitasatoensis. It is active against B. subtilis, S. aureus, M. luteus, and E. coli with MIC values of 0.16, 0...
T36475	TunR2
	TunR2 is an antibiotic and derivative of tunicamycin .1It is active againstB. subtilis(MIC = 0.3 μg/ml) and increases the efficacy of the β-lactam antibiotics oxacillin , methicillin , and penicillin G againstB. subtilis...
T62592	(R)-Gyramide A hydrochloride
	(R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts superhelical activity (IC50: 875 μM). (R)-Gyramide A hydrochloride exhibits antibacterial activity against Pseudomonas aeruginosa E. coli wit...
T37723	IT-143A
	IT-143A is a bacterial metabolite originally isolated fromStreptomycessp. IT-143.1It is active against the bacteriumM. luteus(MIC = 6.25 μg/ml) and the fungiA. fumigatusandT. rubrumin vitro(MICs = 12.5-25 μg/ml). 1.Uraka...
T70642	Lanopepden camsylate
	Lanopepden, also known as GSK-1322322 or GSK-322, is a potent and selective peptide deformylase inhibitor with good in vitro activity against bacteria associated with community-acquired pneumonia and skin infections. GSK...
T80286	TP4 (Nile tilapia piscidin)		Necroptosis
	TP4 (Nile tilapia piscidin) is an orally active piscidin-like antimicrobial peptide that exhibits inhibition of various gram-positive and negative bacterial strains with a minimum inhibitory concentration (MIC) ranging f...		Necroptosis
T36539	Nocardamine
	Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. b...
T35453	β-Defensin-4 (human) (trifluoroacetate salt)
	β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...
T32669	Leucomycin a5	Leukomycin A5,Turimycin H4
	Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg/ml) but not a...
T36659	Boromycin
	Boromycin is a boron-containing macrolide antibiotic that has been found in Streptomyces. Boromycin inhibits growth of B. subtilis (MIC = 0.05 μg/ml) and induces efflux of potassium ions from B. subtilis without affectin...
T37713	Funalenone
	Funalenone is a phenalenone originally isolated from A. niger. It inhibits HIV-1 integrase (IC50 = 10 μM) and HIV-1 replication in human peripheral blood cells transformed by murine leukemia virus (HPB-M(a); IC50 = 1.7 μ...
T79240	DNA gyrase B-IN-2
	DNA gyrase B-IN-2 (Compound E), a 2-aminobenzothiazole derivative, serves as a potent inhibitor of DNA gyrase B with substantial efficacy against ESKAPE pathogens. The compound exhibits potent nanomolar-range inhibition ...
T36409	Roccellic Acid
	Roccellic acid is a lichen secondary metabolite that has been found in R. montagnei and has antibacterial and anticancer activities.1,2 It is active against the bacteria S. gordonii and P. gingivalis (MIC = 46.9 μg/ml fo...
T38009	Kocurin
	Kocurin is a thiazolyl peptide originally isolated fromK. palustrisand has antibiotic activity.1It is active against methicillin-resistantS. aureus(MRSA; MIC = 0.25 μg/ml), as well asB. subtilisandE. faeciumin a solid ag...
T37880	OPC-167832
	OPC-167832 is a potent and orally active dprE1 Inhibitor with an IC50 of 0.258 μM. OPC-167832 has antituberculosis activity and can be used for the research of tuberculosis caused by Mycobacterium tuberculosis[1]. OPC-16...

Compounds

Chlamydia pneumoniae-IN-1

T79088

Synonym:

Target:

2,6-Dichlorodiphenylamine

T38240

Synonym:

Target: Antibacterial

Antitubercular agent-10

Xenopsin precursor fragment

Capreomycin free base

Synonym: Leucomycin A13

(R)-Gyramide A hydrochloride

TP4 (Nile tilapia piscidin)

β-Defensin-4 (human) (trifluoroacetate salt)

Synonym: Leukomycin A5,Turimycin H4

Cat No.	Product Name	Synonyms	Targets
TN4883	Quinine sulfate dihydrate		Others
	Quinine sulfate dihydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassiu...		Others
TN3260	8(14),15-Isopimaradien-3-ol		Calcium Channel , Antifection
	ent-8(14),15-pimaradien-3beta-ol (8(14),15-Isopimaradien-3-ol) can induce vascular relaxation. It displays high antibacterial activities (MIC values lower than 10 microg /mL for most pathogens).		Calcium Channel , Antifection
TN4594	Murraol		Antifection
	Murraol shows the significant proliferative activities on osteoblast-like UMR106 cells lines at the concentration of 1 × 10-10 mol/L. It and auraptenol show 63 ug/mL MIC value against Klebsiella pneumoniae ATCC 4352 and ...		Antifection
TN1099	Dihydroevocarpine		MAO , P-gp , Antifection
	Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a moderate modulator of p-glycoprotein (p-gp) activity; it s...		MAO , P-gp , Antifection
T80335	Maximin H3
	Maximin H3, an antimicrobial peptide from Chinese red belly toad Bombina maxima skin secretions, exhibits antimicrobial properties against Escherichia coli ATCC25922, Staphylococcus aureus ATCC2592, Bacillus pyocyaneus C...
T75697	1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
	1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone, a diacylglycerol acyltransferase inhibitor and angiotensin II receptor blocker, exhibits IC50 values of 20.1 μM and 34.1 μM, respectively. Additionally, it demonstr...
TN4148	Glyasperin C		Tyrosinase , Antifection
	Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidate in the design of skin-whitening agents. Glyasperin C show...		Tyrosinase , Antifection
T35483	19,20-Epoxycytochalasin D
	19,20-Epoxycytochalasin D is a fungal metabolite that has been found in the endophytic fungus Nemania sp. UM10M. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum (MIC = 0.4 ng/ml for...
TN6674	Cyclo-(Pro-Gly)	Cyclo(Pro-Gly)
	Cyclo(Pro-Gly) is an active metabolite of piracetam-N-phenylacetyl-L-prolylglycine (GWS-111), it shows a greater resistance to an enzymatic effect than natural neuropeptides. Cyclo-(Gly-Pro) shows cytotoxicity at the con...
T35409	(+)-δ-Cadinene		Apoptosis , Antibacterial
	(+)-δ-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 μg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 ...		Apoptosis , Antibacterial
T35741	Gliovirin
	Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the pa...

Natural Products

Quinine sulfate dihydrate

TN4883

Synonym:

Target: Others

8(14),15-Isopimaradien-3-ol

TN3260

Synonym:

Target: Calcium Channel, Antifection

Target: MAO, P-gp, Antifection

1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone

Target: Tyrosinase, Antifection

19,20-Epoxycytochalasin D

Synonym: Cyclo(Pro-Gly)

Target: Apoptosis, Antibacterial

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01431	L1CAM Protein, Human, Recombinant (His)	Human	HEK293 Cells
	L1CAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 125 kDa and the accession number is P32004-1.
TMPK-00811	L1CAM Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many huma...
TMPK-00532	CD46 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in prev...
TMPY-02023	CD46 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white bloo...
TMPK-00570	CD46 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in prev...
TMPY-06857	L1CAM Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	L1CAM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 149.93 kDa and the accession number is NP_000416.1.
TMPY-06759	L1CAM Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	L1CAM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 126.46 kDa and the accession number is NP_000416.1.
TMPY-02300	BIN1 Protein, Human, Recombinant (His)	Human	E. coli
	Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicat...
TMPY-01751	DR3/TNFRSF25 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	DR3/TNFRSF25 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-00961	ADAM15 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10.
TMPY-05760	DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.