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(+)-δ-Cadinene

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Catalog No. T35409Cas No. 483-76-1

(+)-δ-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 μg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 and 3 against third instar larvae of A. stephensi, A. aegypti and C. quinquefasciatust, respectively.(+)-δ-Cadinene (10, 50 and 100 μM) induced apoptosis and inhibited the growth of OVCAR-3 human ovarian cancer cells apoptosis and inhibited their proliferation.

(+)-δ-Cadinene

(+)-δ-Cadinene

😃Good
Catalog No. T35409Cas No. 483-76-1
(+)-δ-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 μg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 and 3 against third instar larvae of A. stephensi, A. aegypti and C. quinquefasciatust, respectively.(+)-δ-Cadinene (10, 50 and 100 μM) induced apoptosis and inhibited the growth of OVCAR-3 human ovarian cancer cells apoptosis and inhibited their proliferation.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$14235 days35 days
1 g$57535 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
(+)-δ-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 μg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 and 3 against third instar larvae of A. stephensi, A. aegypti and C. quinquefasciatust, respectively.(+)-δ-Cadinene (10, 50 and 100 μM) induced apoptosis and inhibited the growth of OVCAR-3 human ovarian cancer cells apoptosis and inhibited their proliferation.
Chemical Properties
Molecular Weight204.35
FormulaC15H24
Cas No.483-76-1
ColorTransparent
AppearanceLiquid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 30 mg/mL (146.81 mM), Sonication is recommended.
PBS (pH 7.2): 1 mg/mL (4.89 mM), Sonication is recommended.
Ethanol: 30 mg/mL (146.81 mM), Sonication is recommended.
DMSO: 30 mg/mL (146.81 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (9.79 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
PBS (pH 7.2)/DMF/Ethanol/DMSO
1mg5mg10mg50mg
1 mM4.8936 mL24.4678 mL48.9356 mL244.6782 mL
DMF/Ethanol/DMSO
1mg5mg10mg50mg
5 mM0.9787 mL4.8936 mL9.7871 mL48.9356 mL
10 mM0.4894 mL2.4468 mL4.8936 mL24.4678 mL
20 mM0.2447 mL1.2234 mL2.4468 mL12.2339 mL
50 mM0.0979 mL0.4894 mL0.9787 mL4.8936 mL
100 mM0.0489 mL0.2447 mL0.4894 mL2.4468 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

δ-Cadinenedelta-CadineneBacterialapoptosis(+)δCadinene(+) δ Cadinene
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