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(+)-δ-Cadinene

Catalog No. T35409   CAS 483-76-1

(+)-δ-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 μg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 and 3 against third instar larvae of A. stephensi, A. aegypti and C. quinquefasciatust, respectively.(+)-δ-Cadinene (10, 50 and 100 μM) induced apoptosis and inhibited the growth of OVCAR-3 human ovarian cancer cells apoptosis and inhibited their proliferation.

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(+)-δ-Cadinene Chemical Structure
(+)-δ-Cadinene, CAS 483-76-1
Pack Size Availability Price/USD Quantity
100 mg 35 days $ 98.00
1 g 35 days $ 397.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description (+)-δ-Cadinene is a sesquiterpene from G. hirsutum with antibacterial, insecticidal, anticancer and antiproliferative activities. It showed a MIC value of 31.25 μg/ml against S. pneumoniae and LC50s values of 8.23, 9. 2 and 3 against third instar larvae of A. stephensi, A. aegypti and C. quinquefasciatust, respectively.(+)-δ-Cadinene (10, 50 and 100 μM) induced apoptosis and inhibited the growth of OVCAR-3 human ovarian cancer cells apoptosis and inhibited their proliferation.
Molecular Weight 204.35
Formula C15H24
CAS No. 483-76-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMF: 30 mg/mL

PBS (pH 7.2): 1 mg/mL

Ethanol: 30 mg/mL

DMSO: 30 mg/mL

TargetMolReferences and Literature

1. Meng YL, et al. Coordinated accumulation of (+)-delta-cadinene synthase mRNAs and gossypol in developing seeds of Gossypium hirsutum and a new member of the cad1 family from G. arboreum. J Nat Prod. 1999;62(2):248-252. 2. Yoshikuni Y, et al. Engineering cotton (+)-delta-cadinene synthase to an altered function: germacrene D-4-ol synthase. Chem Biol. 2006;13(1):91-98. 3. Tan XP, et al. Expression pattern of (+)-delta-cadinene synthase genes and biosynthesis of sesquiterpene aldehydes in plants of Gossypium arboreum L. Planta. 2000;210(4):644-651. 4. Chen XY, et al. Cloning and heterologous expression of a second (+)-delta-cadinene synthase from Gossypium arboreum. J Nat Prod. 1996;59(10):944-951.

Related compound libraries

This product is contained In the following compound libraries:
Food as Medicine Compound Library Chinese Pharmacopoeia Natural Product Library PBCRBS Traditional Chinese Medicine Compound Library

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Keywords

(+)-δ-Cadinene 483-76-1 Apoptosis Microbiology/Virology Antibacterial (+)δCadinene delta-Cadinene (+) δ Cadinene δ-Cadinene inhibitor inhibit

 

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