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Search Results for " je "

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T32285	JE-2147	JE2147,AG 1776,AG1776,JE 2147,AG-1776
	JE-2147 belongs to a type of compound known as hybrid peptides. The compound contains at least two different kinds of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
T32286	JE-2178	JE2178
	JE-2178 is compound with high bioavailability .
Fr13138	Jedi2
	Jedi2 is a Piezo1 activator rather than a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a K d of 2770 μM [1].
T34821	Tetrahydrojervine
	Tetrahydrojervine is a bioactive chemical.
T10555	BJE6-106	B106	PKC
	BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM). BJE6-106 induces caspase-dependent apoptosis with tumor-specific effect.		PKC
T3363L	Jervine HCl	Jervine hydrochloride
	Jervine is a naturally occurring steroidal alkaloid derived from the Veratrum plant species. Over the Hedgehog signaling pathway, Jervine effectively inhibits tumor growth using three human tumor xenograft models. Jervin...
T28049	MJE3	MJE 3,MJE-3
	MJE3 is an inhibitor of phosphoglycerate mutase-1 (PGAM1), it displays antiproliferative effects in human breast cancer cells by inhibiting glycolysis.
T79230	JET-209		PROTACs
	JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration (DC50) values of 0.05 nM for CBP and 0.2 nM for p300. The compound comprise...		PROTACs
T131628	Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin)
	Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin) is a useful organic compound for research related to life sciences and the catalog number is T131628.
T32287	Jegosapogenol A	Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D
	Jegosapogenol A is a type of triterpenoid. Triterpenoids are terpene molecules containing six isoprene units. Barringtogenol C is a very weakly acidic compound (based on its pKa) and practically insoluble (in water). Bar...
T31415	Diacetyljervine	NSC-406352,NSC 406352,N-acetyl-,N,O-Diacetyljervine,Jervine,NSC406352
	Diacetyljervine is a bioactive chemical.
T33767	O-Acetyljervine	3-O-Acetyljervine
	O-Acetyljervine is a bioactive chemical.

Compounds

JE-2147

T32285

Synonym: JE2147,AG 1776,AG1776,JE 2147,AG-1776

Synonym: Jervine hydrochloride

Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin)

Synonym: Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D

Target:

Diacetyljervine

T31415

Synonym: NSC-406352,NSC 406352,N-acetyl-,N,O-Diacetyljervine,Jervine,NSC406352

Target:

O-Acetyljervine

T33767

Synonym: 3-O-Acetyljervine

Target:

Cat No.	Product Name	Synonyms	Targets
TN2343	Pseudojervine	Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine	Platelet aggregation
	Pseudojervine (O-beta-D-Glucopyranosyljervine) is derived from Veratrum nigrum L. Pseudojervine exhibits feeble inhibition activity against platelet aggregation.		Platelet aggregation
T3250	Royal Jelly acid	10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid	VEGFR , Endogenous Metabolite
	Royal Jelly acid (Queen Bee Acid) is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.		VEGFR , Endogenous Metabolite
T3363	Jervine	Iervin,11-Ketocyclopamine,Jerwiny	Hedgehog/Smoothened , Smo
	The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signa...		Hedgehog/Smoothened , Smo
T22311	Djenkolic Acid	jengkolic acid,Djenkolate,S,S'-Methylenebiscysteine	Others
	Djenkolic Acid (S,S'-Methylenebiscysteine) is a naturally occurring sulfur-containing amino acid extracted from djenkol beans(Archidendron pauciflorum), which is native to Southeast Asia. It is an uncommon but important ...		Others
TN2813	23-deoxojessic acid		Others
	23-Deoxojessic acid possesses strong cytotoxicity towards highly liver metastatic murine colon 26-L5 carcinoma cells, with ED50 values equal to or less than 6 microM.		Others
T82009	Jervinone
	Jervinone, an alkaloid metabolite derived from Veratrum, is isolated from the mold Cunninghamella echinulata [1].
TN5935	1-Dehydroxy-23-deoxojessic acid	3-Hydroxy-24-methylenecycloartan-28-oic acid
	1-Dehydroxy-23-deoxojessic acid is a natural product for research related to life sciences. The catalog number is TN5935 and the CAS number is 149252-87-9.
T24198	Jesaconitine	BRN0075405,BRN-0075405,BRN 0075405,Diesaconitine
	Jesaconitine is an Aconitine analog.
TN3805	Dehydrogeijerin		NOS , MAPK , COX
	Dehydrogeijerin significantly inhibits the inflammatory activity of activated macrophages, suggesting that it could be a potential candidate for the treatment of inflammatory disease.		NOS , MAPK , COX

Natural Products

Pseudojervine

TN2343

Synonym: Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine

Target: Platelet aggregation

Royal Jelly acid

T3250

Synonym: 10-Hydroxy-trans-2-decenoic acid,10-Hydroxy-2-decenoic acid,10H2DA,10-Hydroxy-2-decylenic acid,Queen Bee Acid,(E)-10-Hydroxy-2-decenoic acid

Target: VEGFR, Endogenous Metabolite

Jervine

T3363

Synonym: Iervin,11-Ketocyclopamine,Jerwiny

Target: Hedgehog/Smoothened, Smo

Djenkolic Acid

T22311

Synonym: jengkolic acid,Djenkolate,S,S'-Methylenebiscysteine

1-Dehydroxy-23-deoxojessic acid

TN5935

Synonym: 3-Hydroxy-24-methylenecycloartan-28-oic acid

Target:

Jesaconitine

T24198

Synonym: BRN0075405,BRN-0075405,BRN 0075405,Diesaconitine

Target: NOS, MAPK, COX

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00028	CCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equ...
TMPY-00606	MCP-1/CCL2 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	MCP-1/CCL2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148.
TMPY-05653	MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	Baculovirus Insect Cells
	MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148.
TMPJ-00009	CCL2 Protein, Human, Recombinant	Human	E. coli
	The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for mono...
TMPH-00326	Flagellin A Protein, Campylobacter jejuni, Recombinant (His)	Campylobacter jejuni	E. coli
	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin A Protein, Campylobacter jejuni, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The...
TMPH-02338	HFBII Protein, Hypocrea jecorina, Recombinant (B2M & His & JD)	Hypocrea jecorina	E. coli
	Responsible for spore hydrophobicity and protection. HFBII Protein, Hypocrea jecorina, Recombinant (B2M & His & JD) is expressed in E. coli expression system with N-10xHis-B2M-JD tag. The predicted molecular weight is 12...
TMPH-02316	YJEFN3 Protein, Human, Recombinant	Human	E. coli
	May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endotheli...
TMPH-02354	Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO)	H1N1	E. coli
	Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be l...
TMPY-00273	Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA1 Protein (His)	H1N1	HEK293 Cells
	Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is C7RWT2.
TMPY-00056	Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA Protein (His)	H1N1	Baculovirus Insect Cells
	Influenza A H1N1 (A/NewJersey/8/1976) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.9 kDa and the accession number is C7RWT2.
TMPH-00328	Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His)	Campylobacter jejuni	E. coli
	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His) is expressed in E. coli expression system with C-6xHis ta...
TMPH-00327	Flagellin A Protein, Campylobacter jejuni, Recombinant	Campylobacter jejuni	E. coli
	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin A Protein, Campylobacter jejuni, Recombinant is expressed in E. coli expression system. The predicted molecular we...
TMPY-03352	Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA Protein (His)	H7N2	Baculovirus Insect Cells
	Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is C6KLK6...
TMPH-02337	Hydrophobin-1 Protein, Hypocrea jecorina, Recombinant (His & SUMO)	Hypocrea jecorina	E. coli
	Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures. Hydrophobin-1 Pro...
TMPY-00422	Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA1 Protein (His)	H7N2	HEK293 Cells
	Influenza A H7N2 (A/ruddy turnstone/New Jersey/563/2006) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is C6KLK6.