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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16028 | IMB-XH1 | Mcl1-IN-2 | BCL , Antibacterial |
IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor. | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
T6157 | Devimistat | CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid | Apoptosis , Dehydrogenase , Mitochondrial Metabolism |
Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potent... | |||
TN3655 | Cimiside E | ERK , TNF , ROS , Akt , PI3K , PKC , PPAR | |
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may b... | |||
T81524 | Peimisine 3-O-β-D-glucopyranoside | ||
Peimisine 3-O-β-D-glucopyranoside (Compound 1), a steroid alkaloid, is isolated and purified from Fritillaria unibracteata and demonstrates a moderate protective effect against rotenone-induced neurotoxicity in the PC12 ... | |||
T13614 | Cimiside B | Others | |
Cimiside B is a glycoside alkaloid isolated from the rhizome of Cimicifuga dahurica. | |||
T7348 | Imisopasem manganese | M40403 | Others |
Imisopasem manganese (M40403) is a manganese superoxide MnSOD non-peptidyl mimetic. | |||
T74219 | Maximiscin | ||
Maximiscin, a metabolite derived from fungi, causes DNA damage and exhibits selective cytotoxic activity towards a specific subtype of triple-negative breast cancer. | |||
T69482 | MßL-IN-2I | ||
MßL-IN-2I is a potent broad-spectrum metallo-β-lactamase (MβL) inhibitor which inhibits the MβLs NDM-1, VIM-2, ImiS, and L1. | |||
T60914 | Metallo-β-lactamase-IN-8 | ||
Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum metallo-β-lactamases (MβLs) inhibitor with antibacterial activity. The IC50 values of Metallo-β-lactamase-IN-8 against L1, Imi... |