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Search Results for " irak1 "

11

Compounds

Cat No. Product Name Synonyms Targets
T9203 JH-X-119-01 IRAK
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1.
T14367 AZ1495 IRAK , CDK , Haspin Kinase
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffu...
T2457 IRAK-1-4 Inhibitor I IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor IRAK
IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.
TN1134 Euscaphic acid Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T62209 HS-276 MAPK
HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM). HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used ...
T9631 IRAK-4 protein kinase inhibitor 2 IRAK
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).
T78054 JNJ-1013 Apoptosis
JNJ-1013 is a potent and selective IRAK1 degrader, demonstrating IC50 values of 72 nM for IRAK1, 443 nM for IRAK4, and 1071 nM for VHL FP. It induces apoptosis and augments the expression of cleaved PARP while decreasing...
T71548 JH-I-25
JH-I-25 is an IRAK1 kinase inhibitor.
T75113 GLPG2534 GLPG-2534 IRAK
GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 inhibits human and mouse IRAK4 and could be used to study psoriasis and atopic dermatitis.
T40225 JH-X-119-01 hydrochloride
JH-X-119-01 hydrochloride is a potent and selective inhibitor of interleukin-1 receptor-associated kinases 1 (IRAK1). It effectively alleviates lipopolysaccharide (LPS)-induced sepsis in mice.
T22376 NCGC1481 Others
NCGC1481 is a potent inhibitor of FLT3 and IRAK1/4 with improved stability, solubility, and permeability properties.
TargetMol