forskolin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2939	Forskolin	Coleonol,Colforsin	FXR , Adenylyl cyclase , AChR , Autophagy
	Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the...		FXR , Adenylyl cyclase , AChR , Autophagy
TN4073	Forskolin G		Others
	Forskolin is known to elevate intracellular cAMP levels.		Others
TN4074	Forskolin J		Others
	Forskolin J is a natural product for research related to life sciences. The catalog number is TN4074 and the CAS number is 81873-08-7.		Others
T24365	L 858051	7B-Forskolin,L858051,Dmpb-forskolin,L-858051
	L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.
TN1520	Isoforskolin	Coleonol B	IL Receptor , TNF
	Isoforskolin is derived from Coleus forskohlii and reduces the secretion of TNF-α, IL-1β, IL-6 and IL-8 in human mononuclear leukocytes. Isoforskolin can be used in studies about the treatment of Lyme arthritis.		IL Receptor , TNF
T22467	1,9-Dideoxyforskolin		Others
	The compound is an inactive analog of forskolin(an adenylyl cyclase activator).		Others
T36720	Deacetylforskolin
	Deacetylforskolin is a diterpene and a derivative of forskolin that has been found inC. forskohliiand has diverse biological activities.1,2,3,4It activates rat adipocyte adenylyl cyclase (IC50= 20 μM) and inhibits glucos...
T16516	PG01	Phenylglycine-01	CFTR
	PG01 is a potent CFTR Cl-channel potentiator, effective against ΔF508 (Ka 0.3 μM), and also against E193K, G970R and G551D (CFTR mutants), with Kd values of 0.22 μM, 0.45 μM and 1.94 μM, respectively.PG01 increases ΔF508...		CFTR
TP2092L	Apelin-17 (human, bovine) acetate	Apelin-17 (human, bovine) acetate(217082-57-0 free base)	HIV Protease
	Apelin-17 (human, bovine) acetate is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).		HIV Protease
T5081	Adenine monohydrochloride hemihydrate	Adenine hydrochloride hydrate,6-Aminopurine hydrochloride hydrate	Endogenous Metabolite , Adenosine Receptor
	Adenine monohydrochloride hemihydrate is a high affinity adenine receptor agonist (Ki = 18 nM at rat adenine receptor). It inhibits forskolin-stimulated cAMP formation in CHO cells transfected with the adenine receptor a...		Endogenous Metabolite , Adenosine Receptor
TP1922L1	ELA-11 (human) acetate(1784687-32-6 free base)		Apelin receptor , Arrestin
	ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.		Apelin receptor , Arrestin
TP1936L1	RFRP3(human) acetate(311309-27-0 free base)		Neuropeptide Y Receptor
	RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a NPFF1 receptor agonist, it inhibits forskolin-induced produ...		Neuropeptide Y Receptor
T39392L	C-Type Natriuretic Peptide (CNP) (1-22), human acetate	C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)	Others
	C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), huma...		Others
TP1187	C-Type Natriuretic Peptide (CNP) (1-22), human	CNP (1-22), human	RAAS
	C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide.		RAAS
T10591L	(R)-BPO-27		CFTR , Autophagy
	(R)-BPO-27 is an orally active and potent ATP-competitive CFTR inhibitor (IC50: 4 nM) for the study of diarrhoea and polycystic kidney.		CFTR , Autophagy
T33214	Manoyl oxide	Manoyl
	Manoyl oxide is a proposed intermediate in the biosynthesis of forskolin and other medically important labdane-type terpenoids.
T78083	CB-25		Cannabinoid Receptor
	CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cells [1].		Cannabinoid Receptor
T27779	L-759,656	L 759,656,L759,656
	L-759,656 is highly selective CB2 receptor agonist (CB1 Ki = 4888 nM, CB2 Ki = 11.8 nM). L-759,656 potently inhibits forskolin-stimulated cAMP production in CHO cells (EC50 = 3.1 nM).
TP2092	Apelin-17(human, bovine)	Apelin-17 (human, bovine)
	Endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).
TP1922	ELA-11(human)	ELA-11 (human)
	High affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.