fmk — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TQ0310	FMK		S6 Kinase
	FMK is an irreversible inhibitor of RSK2 kinase.		S6 Kinase
T7020	Z-VAD-FMK	Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD	Caspase
	Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases with irreversible properties. Z-VAD-FMK binds to activated caspases, thereby inhibiting apoptosis.		Caspase
T6013	Z-VAD(OMe)-FMK	Z-VAD-FMK,Z-Val-Ala-Asp(OMe)-FMK	Caspase
	Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a broad-spectrum inhibitor of caspases that is cell-permeable and irreversible. Z-VAD(OMe)-FMK binds to activated caspases, thereby inhibiting apoptosis.		Caspase
T7019	Z-IETD-FMK	Z-IE(OMe)TD(OMe)-FMK,Caspase-8 Inhibitor	Caspase
	Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.		Caspase
T15303	FMK 9a		Cysteine Protease , Autophagy
	FMK 9a is an irreversible inhibitor of ATG4B with IC50 values of 80 and 73 nM in the TR-FRET and cellular-based LRA assays.		Cysteine Protease , Autophagy
T6005	Z-DEVD-FMK	Caspase-3 Inhibitor	Caspase
	Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10.		Caspase
T21835	Z-LEHD-fmk		Apoptosis , Caspase
	Z-LEHD-FMK is a selective and potent caspase-9 inhibitor that protects against reperfusion injury and slows apoptosis.Z-LEHD-FMK exhibits antitumor and neuroprotective activity, increases the yield of in vitro-produced p...		Apoptosis , Caspase
TP1466	Z-YVAD-FMK		Caspase
	AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.		Caspase
T6738	Z-FA-FMK		SARS-CoV , Cysteine Protease
	Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.		SARS-CoV , Cysteine Protease
T10580	BOC-D-FMK		Apoptosis , Caspase
	Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 µM).		Apoptosis , Caspase
T36331	Z-AEVD-FMK	Z-AEVD-FMK,Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone
	Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases.[1] At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its activ...
T11310	FMK-MEA		Others
	FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.		Others
T39344	Z-VDVA-(DL-Asp)-FMK
	Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.
T10548	Biotin-VAD-FMK		Caspase
	Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled inhibitor of caspase. It is used to identify active caspases in cell lysates.		Caspase
TP2161	Z-WEHD-FMK		Caspase
	Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).		Caspase
T40602	Z-LEHD-FMK TFA
	Z-LEHD-FMK TFA is a specific and irreversible inhibitor of caspase-9, offering protection against detrimental reperfusion injury and moderating apoptosis. Additionally, Z-LEHD-FMK TFA demonstrates its neuroprotective pot...
TP1014	Z-VRPR-FMK (TFA)	VRPR
	Z-VRPR-FMK (TFA) (VRPR) is a tetrapeptide and a selective and irreversible inhibitor of lymphoma translocation protein 1 (MALT1) in mucosa-associated lymphoid tissue.
T23555	Z-VEID-FMK		Others
	When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor of Z-Val-Ala-Asp (OMe)-fluoromethy ketone (Z-VAD-FMK) or the caspase 6 inhibitor Z-V...		Others
TP2037	Z-DQMD-FMK
	Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.
T38469	(Rac)-Z-Phe-Phe-FMK	Cathepsin L-IN-2	Beta Amyloid , Cysteine Protease
	(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .		Beta Amyloid , Cysteine Protease