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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $106 | Backorder | |
5 mg | $282 | Backorder | |
10 mg | $468 | Backorder | |
25 mg | $747 | Backorder |
Description | When compared to other caspase inhibitors, Z-DRHD-FMK inhibited caspase 6 activity more effectively than the general caspase inhibitor of Z-Val-Ala-Asp (OMe)-fluoromethy ketone (Z-VAD-FMK) or the caspase 6 inhibitor Z-Val-Glu(Ome)-Ile-Asp(OMe)-fluorometh |
In vitro | The caspase-6-specific inhibitor Z-VEID- FMK and general caspase inhibitors significantly prevent apoptosis of caspase-6-microinjected neurons2. Z-VEID-FMK, which inhibits caspase-6, was also able to abolish the cleavage of procaspase-8, although caspase-6 is activated downstream of caspase-8 in Fas-mediated apoptosis3. |
Molecular Weight | 652.71 |
Formula | C31H45FN4O10 |
Cas No. |
Storage | keep away from moisture|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: ≥113.4 mg/mL |
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