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Search Result

Search Results for " ers "

20

Compounds

Cat No. Product Name Synonyms Targets
T74225 ROS-ERS inducer 1
ROS-ERS inducer 1, a type II immunogenic cell death (ICD) inducer, is a Pt(II)-N-heterocyclic carbene (Pt(II)-NHC) complex derived from 4,5-diarylimidazole. It induces endoplasmic reticulum stress (ERS) along with reacti...
T13416 ZX-29 ALK
ZX-29 is a potent and selective inhibitor of ALK(IC50 of 2.1 nM, 1.3 nM and 3.9 nM for ALK, ALK L1196M and ALK G1202R mutations, respectively), and also induces protective autophagy and has antitumor effect.
T8934 (6R)-FR054 FR054 Apoptosis , Others
(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.
T67943 RORγ inverse agonist 1
RORγ inverse agonist 1 has anti-inflammatory activity and can be used to treat rheumatism and psoriasis.
T68023L Tolnapersine TFA Tolnapersine TFA(70312-00-4 Free base) Dopamine Receptor , Adrenergic Receptor
Tolnapersine TFA is a mixed dopamine agonist and alpha adrenergic receptor antagonist.
TP2417 Tidembersat Others
Tidembersat is a small molecule compound used to treat and/or prevent degenerative diseases such as Huntington's chorea, schizophrenia, neurological.
T39979 (S)-ErSO Others
(S)-ErSO is an inactive dextrorotatory enantiomer of ErSO.
T3246 Tabersonine (-)-Tabersonine,Tabersonin Others
Tabersonine (Tabersonin)is a terpene indole alkaloid found in the medicinal plant Catharanthus roseus.
T9297 Perseitol Others
Perseitol is a sugar that is specific to avocado honey. Perseitol have recently been reported as candidate biomarkers for avocado intake.
T7578 REVERSE T3 3,3',5'-triiodo-L-thyronine Thyroid hormone receptor(THR)
Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
T10694 CB1 inverse agonist 1 MRL-650 Cannabinoid Receptor
CB1 inverse agonist 1 (MRL-650) is an orally active and selective CB1 agonist. The IC50s for CB1 and CB2 are 7.5 nM and 4100 nM, respectively. CB1 inverse agonist 1 shows anorexigenic effects.
T5463 Verdiperstat AZD3241,AZD 3241 Glutathione Peroxidase
Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.
T31532 Disperse Red 1 Celliton Scarlet B,Neosetile Scarlet B,Diacelliton Scarlet B,Fenacet Scarlet B,Celliton Red B Others
Disperse Red 1 (Celliton Scarlet B) is an azo dye that contributes to the toxicity and pollution of wastewater.
T9099 Disperse Fast Yellow 4K Disperse Yellow Others
Disperse Fast Yellow 4K (Disperse Yellow) is a color additive used in dyes.
T70084 Dersalazine Dersalazine Free Base IL Receptor , Platelet aggregation
Dersalazine (Dersalazine Free Base), an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential effic...
T7700 Lersivirine Lersivirine(UK 453061),UK-453061 HIV Protease , Reverse Transcriptase
Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.
T9623 RORγt inverse agonist 13 ROR
RORγt inverse agonist 13 (Compound 3i) is a potent, orally active and selective RORγt inverse agonist (IC50=63.8 nM), with improved drug-like properties[1].
T4994 Tocofersolan Others
Tocofersolan (TPGS) is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pedia...
T64377 AGI-41998 tautomers Others
AGI-41998 tautomers is a tautomerism of pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-. pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-...
T39980 ErSO Others
ErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer.
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