ccl2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8381	Amodiaquine		Others , Histone Methyltransferase , Parasite
	Amodiaquine is a synthetic aminoquinoline, used to treat malaria.		Others , Histone Methyltransferase , Parasite
T8494	NS-3-008 hydrochloride	NS-3-008 HCl	Others
	NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).		Others
T0381	Amodiaquine dihydrochloride dihydrate	Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate	Histone Methyltransferase , Parasite , Histamine Receptor
	Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.		Histone Methyltransferase , Parasite , Histamine Receptor
T6413	Bindarit	AF2838	CCR
	Bindarit (AF2838) displays specific inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.		CCR
T2386	Pirfenidone	S-7701,AMR-69,S-7701,AMR69	CCR , TGF-beta/Smad
	Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum...		CCR , TGF-beta/Smad
T12485	Pirfenidone-d5	AMR69 D5,Pirfenidone D5	Others
	Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells.		Others
T19854	Evoxine
	Evoxine is a selective inhibitor of CO2-induced immune suppression. It inhibits hypercapnic suppression of interleukin-6 and the chemokine CCL2 expression in human THP-1 macrophages.
T76740	Carlumab
	Carlumab (CNTO 888), a humanized antibody with high affinity for CCL2 (chemokine ligand 2), is employed in cancer research, notably in the study of prostate cancer [1].
T64256	Emapticap pegol
	Emapticap pegol is a pro-inflammatory chemokine C-C motif ligand 2 (CCL2) inhibitor. emapticap pegol is also a 40-nucleotide oligonucleotide aptamer that exhibits different forms of Spiegelmers (L-RNA aptamers) in human ...
T62321	ST247
	ST247 is a potent PPARβ/δ inverse agonist with a high affinity for PPARβ/δ and is able to inversely regulate the expression of the activation marker CCL2. ST247 inhibits agonist-induced transcriptional activity of PPARβ/...
TN3614	Cearoin		ERK , BCL , PARP , IκB/IKK , TNF , NF-κB , ROS , Caspase
	Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the expression of iNOS mRNA and LPS-induced mRNA expression of...		ERK , BCL , PARP , IκB/IKK , TNF , NF-κB , ROS , Caspase
T72970	Rosolic Acid
	Rosolic Acid serves as an Nrf2 activator and influences its downstream targets, enhancing angiogenic factor levels while reducing inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). This compound not ...
T71306	Gemfibrozil-d6
	Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil redu...
T83698	Cathelicidin-2 (128-153) (chicken) TFA	Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)
	Cathelicidin-2 (CATH-2) (128-153) is a synthetic antimicrobial peptide derived from amino acids 128-153 of chicken CATH-2, demonstrating activity against pathogens such as E. coli, S. aureus, S. enteritidis, and B. globi...
T35463	(±)14(15)-EET	(±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
	(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) i...
T35453	β-Defensin-4 (human) (trifluoroacetate salt)
	β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...
T35452	β-Defensin-3 (human) (trifluoroacetate salt)
	β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ...
T37289	Resolvin D2 n-3 DPA	Resolvin D2 n-3 DPA
	Resolvin D2 n-3 DPA (RvD2 n-3 DPA) is a specialized pro-resolving mediator (SPM).1It is formed from docosapentaenoic acid , an intermediate in the conversion of eicosapentaenoic acid to docosahexaenoic acid , in human le...
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...