cyp2c19 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T63337	CYP2C19-IN-1
	CYP2C19-IN-1 is a potent, non-genotoxic, non-hepatotoxic inhibitor of CYP2C19. CYP2C19-IN-1 inhibits RNA-dependent RNA polymerase (RdRP) (Ki: 6.16 μM) and can be used to study Zika virus (ZIKV) infection.
T63495	CYP2C1/CYP2C19-IN-2
	CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.
T63496	CYP2C9/CYP2C19-IN-1
	CYP2C9/CYP2C19-IN-1 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.
T21529	(S)-Mephenytoin		Others
	(S)-Mephenytoin ((+)-Mephenytoin) anticonvulsant effect. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19 and can be used to analyze cytochrome P450 metabolism.		Others
T3610	Ranitidine	HSDB 3925,Ranitidin	P450 , Antibacterial , Histamine Receptor
	Ranitidine (HSDB 3925) is a non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers.		P450 , Antibacterial , Histamine Receptor
T21425	Mephenytoin	Mesantoin,Methoin,Insulton,Phenantoin,Methylphenetoin	P450
	Mephenytoin (Phenantoin) is an anticonvulsant and a substrate of CYP2C19 and CYP2B6.		P450
T0865	Ranitidine Hydrochloride	AH19065	P450 , Antibacterial , Histamine Receptor
	Ranitidine Hydrochloride (AH19065) is a member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enteroc...		P450 , Antibacterial , Histamine Receptor
T4190	Ticlopidine	PCR 5332,Ticlid	ATPase , Adiponectin receptor
	Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.		ATPase , Adiponectin receptor
T21029	Norfluoxetine Hydrochloride	Norfluoxetine HCl	Others
	Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.		Others
T0182L	Clopidogrel hydrogen sulfate	(S)-(+)-Clopidogrel hydrogen sulfate,(S)-(+)-Clopidogrel bisulfate,SR-25990C,Clopidogrel	P450 , P2Y Receptor
	Clopidogrel hydrogen sulfate ((S)-(+)-Clopidogrel bisulfate) , a selective, high-affinity P2Y12 receptor antagonist, suppressess fibrinogen binding to platelets and platelet adhesion and aggregation.		P450 , P2Y Receptor
T67926	(S)-(+)-N-3-Benzylnirvanol	ZSN-76403	P450 , HIV Protease
	(S)-(+)-N-3-Benzylnirvanol (ZSN-76403) is a cytochrome P450 CYP2C19 inhibitor with an IC50 value of 0.179 µM that can be used to study HIV infection.		P450 , HIV Protease
T4498	Stiripentol	BCX2600,Diacomit	P450
	Stiripentol (BCX2600) (STP) is an anticonvulsant agent, which can inhibit N-demethylation of CLB to NCLB mediated by CYP3A4 (noncompetitively) and CYP2C19 (competitively) with Ki of 1.59/0.516 μM and IC50 of 1.58/3.29 μM...		P450
T37332	(±)-N-3-Benzylnirvanol		P450
	(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll. (+) -n-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll are selective inhibitors of cytochrome P450 that inhibit CYP2C19, a...		P450
T22391	Omeprazole Sodium		P450 , Proton pump , Antibacterial , Autophagy
	Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive...		P450 , Proton pump , Antibacterial , Autophagy
T10147	4-Hydroxymephenytoin	(+/-)-4'-Hydroxymephenytoin	Others , Drug Metabolite
	4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.		Others , Drug Metabolite
T9335	1,1'-Methylenedi-2-naphthol	Squoxin	Others
	1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).		Others
T10138	4-Desmethoxy Omeprazole		Drug Metabolite
	4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole is a proton pump inhibitor (PPI). Omeprazole shows competitive inhibition of CYP2C19 activity (Ki: 2 to 6 μM).		Drug Metabolite
T3818	Fraxinol		Others , P450
	Fraxinol is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 5, 7-dimethoxy-2h-chromen-2-one. It is generated by cyp1a2, cyp2a6, cyp2b6, cyp2c9, cyp2c19, and cyp2e1 enzymes via an...		Others , P450
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T20570	Labetalol	Apo-Labetalol,Albetol,Trandate,Dilevalol,Normodyne	Adrenergic Receptor
	Labetalol (Apo-Labetalol) is a mixed alpha/beta-adrenergic antagonist.It is used to treat high blood pressure. It can be given by mouth for long term hypertension management or intravenously in severe hypertensive situat...		Adrenergic Receptor