chikv — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9394	CHIKV-IN-2		Dehydrogenase
	CHIKV-IN-2, a chemical compound, exhibits potent inhibitory activity against the enzyme Dihydroorotate Dehydrogenase (DHODH), crucial for pyrimidine synthesis affecting various viruses' replication. It serves as an effec...		Dehydrogenase
T61675	CHIKV-IN-3
	CHIKV-IN-3 is a potent inhibitor effective against two low-passage CHIKV strains, demonstrating EC50 values of 1.55 μM for CHIKV-122508 and 0.14 μM for CHIKV-6708, respectively. It operates by targeting host cells to dis...
T10835	Cletoquine	Desethylhydroxychloroquine	Parasite , Antifection
	Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatme...		Parasite , Antifection
TN3500	Beta-Amyrone	β-Amyron	COX , AChR , PPAR , Antifection
	beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a...		COX , AChR , PPAR , Antifection
T8498	EIDD-1931	Beta-d-N4-hydroxycytidine	Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
	EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndr...		Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
T10835L1	Cletoquine hydrochloride	Cletoquine hydrochloride( 4298-15-1 Free base)	Influenza Virus , Parasite
	Cletoquine hydrochloride is a major active metabolite of Hydroxychloroquine. Cletoquine hydrochloride is a Chloroquine derivative and exhibits the ability to against the chikungunya virus (CHIKV). Cletoquine hydrochlorid...		Influenza Virus , Parasite
T10835L	Cletoquine oxalate	Desethylhydroxychloroquine oxalate	Others
	Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has...		Others
T36880	NHC-diphosphate
	NHC-diphosphate, a phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) in its diphosphate form[1], serves as a potent antiviral agent. As a pyrimidine ribonucleoside, NHC effectively counters the repl...
T38861	Tat-beclin 1
	Tat-beclin 1, a peptide derived from the autophagy protein beclin 1, is a powerful inducer of autophagy. It interacts with GAPR-1 (GLIPR2), a negative regulator of autophagy. Tat-beclin 1 effectively reduces the buildup ...
T76058	Tat-beclin 1 TFA
	Tat-beclin 1 TFA, a peptide originating from a segment of the autophagy protein beclin 1, effectively initiates autophagy and engages with the autophagy negative regulator, GAPR-1 (GLIPR2). It notably reduces the buildup...