bec — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6779	BEC hydrochloride	BEC HCl	Arginase
	BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II, and is 0.4-0.6 μM for rat Arginase I.		Arginase
T6140	SB-334867 free base	SB334867A free base,SB-334867,SB 334867,SB334867	OX Receptor
	SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist.		OX Receptor
T1249	Beclamide	N-Benzyl-3-chloropropionamide,Chloracon,Chlorakon	Others
	Beclamide (Chlorakon) (N-benzyl-B-chloropropionamide) is a drug that possesses anticonvulsant activity. It is no longer used. It has been used as a sedative and as an anticonvulsant. It was studied in the 1950s for its a...		Others
T1127	Beclometasone dipropionate	Beclovent,Beclomethasone dipropionate,Beconase,Vancenase	Glucocorticoid Receptor
	Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone...		Glucocorticoid Receptor
T38861L	Tat-beclin 1 acetate	Tat-beclin 1 acetate(1423821-88-8 free base)	HIV Protease , Autophagy
	Tat-beclin 1 acetate is a potent inducer of autophagy and interacts with the negative regulator of autophagy, GAPR-1. Tat-beclin 1 acetate decreases the accumulation of polyglutamine expansion protein aggregates and the ...		HIV Protease , Autophagy
T17155	Trabectedin	Ecteinascidin 743,ET-743	Apoptosis , Reactive Oxygen Species
	Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0...		Apoptosis , Reactive Oxygen Species
T61151	Beclobrate
	Beclobrate (Sgd 24774), a fibric acid derivative, exhibits potent lipid-lowering efficacy in rodent models [1].
TQ0238	Lanabecestat	LY3314814,AZD3293	BACE
	Lanabecestat (AZD3293) is a highly potent and highly permeable, orally active BACE1 inhibitor (Ki: 0.4 nM) that crosses the blood-brain barrier, Lanabecestat can be used for the study of neurological diseases like Alzhei...		BACE
T13253	Umibecestat	CNP520	BACE
	Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of al...		BACE
T7011	Verubecestat	MK-8931	Beta-Secretase , BACE
	Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.		Beta-Secretase , BACE
T11175	Elenbecestat	E2609	Beta-Secretase , BACE
	Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.		Beta-Secretase , BACE
T67988	Embeconazole	R 120758,CS 758	Antifungal
	Embeconazole (R 120758) is a triazole antifungal agent.Embeconazole has strong in vitro activity against clinically important fungi such as Candida, Aspergillus and Cryptococcus neoformans.		Antifungal
T10493	Beclabuvir	BMS-791325	Others
	Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the HCV NS5B RNA-dependent RNA polymerase. It inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 (IC50 < 28 nM).		Others
T72910	APOBEC3G-IN-1		Others
	APOBEC3G-IN-1 (MN136.0185) is a targeted APOBEC3G inhibitor with anti-HIV activity for the study of infectious diseases and cancer.		Others
T8777	Beclometasone	BecloMethasone	Glucocorticoid Receptor
	Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.		Glucocorticoid Receptor
T14338	Atabecestat	JNJ-54861911	BACE
	Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a ...		BACE
T76058	Tat-beclin 1 TFA
	Tat-beclin 1 TFA, a peptide originating from a segment of the autophagy protein beclin 1, effectively initiates autophagy and engages with the autophagy negative regulator, GAPR-1 (GLIPR2). It notably reduces the buildup...
T80574	Becotatug	JMT-101	EGFR
	Becotatug (JMT-101) is an IgG1 antibody that targets EGFR and can be conjugated to Afatinib and Osimertinib, functioning as a synthetic antibody-drug conjugate (ADC) [1].		EGFR
T63801	Beclometasone dipropionate monohydrate
	Beclometasone dipropionate monohydrate is a precursor drug to Beclometasone, an orally active glucocorticoid receptor agonist that agonizes the glucocorticoid receptor and inhibits inflammation and hyperproliferation. mo...
T60993	Alpibectir
	Alpibectir has antibacterial activity [1].