Powder: -20°C for 3 years | In solvent: -80°C for 2 years
Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 5 days | $ 148.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 456.00 |
Description | Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction and it is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment[1]. |
Synonyms | JNJ-54861911 |
Molecular Weight | 367.4 |
Formula | C18H14FN5OS |
CAS No. | 1200493-78-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
DMSO: 250 mg/mL (680.46 mM), Need ultrasonic
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Atabecestat 1200493-78-2 Neuroscience BACE JNJ-54861911 inhibitor inhibit