20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6501 | Fludarabine Phosphate | NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl... | |||
T1506 | Vidarabine | Adenine Arabinoside,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A | Nucleoside Antimetabolite/Analog , Tyrosine Kinases , DNA/RNA Synthesis , Antibiotic , HSV |
Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and signific... | |||
T1038 | Fludarabine | NSC 118218,Fludarabinum,F-ara-A | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , STAT |
Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and... | |||
T10360 | AR-A 2 | AR-A 000002 | Others |
AR-A 2 is a selective 5-HT1B receptor antagonist, with a high affinity to guinea pig cortex 5HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki: 0.24 and 0.47 nM) and with 10-fold lower affinity to guinea pig 5-HT1D... | |||
T19688 | Lodenosine | FddA,3'-dideoxyarabinosyladenine,Fddl,2'-F-dd-ara-A,2'-Fluoro-2',DDG-1 | |
Lodenosine is an inhibitor of RNA-directed DNA polymerase, and potentially for the treatment of HIV. | |||
TNU1171 | 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite | ||
2'-Fluoro-2'-deoxy-ara-A(Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite; Nucleoside Derivative - Fluoro-modified nucleoside. | |||
T27342L | Flurocitabine HCl | Flurocitabine HCl(37717-21-8 Free base) | Others |
Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).Flurocit... | |||
T1272 | Cytarabine | Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV |
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity. | |||
T36944 | Ara-G | Nucleoside Antimetabolite/Analog | |
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate... | |||
T1272L | Cytarabine hydrochloride | Ara-C hydrochloride,Cytosine Arabinoside hydrochloride | DNA/RNA Synthesis |
Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ... | |||
T8308 | NL-1 | Mitochondrial Metabolism , Autophagy | |
NL-1 is a mitoNEET inhibitor with antileukemic effect. | |||
T30117 | Ara-fluorocytosine | NSC529180,NSC 529180,NSC-529180 | |
Ara-fluorocytosine is a biochemical. | |||
TNU1173 | 2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite | ||
2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite is a Nucleoside Phosphoramidite; Nucleoside Derivative - Fluoro-modified nucleoside. | |||
T74032 | Ara-F-NAD+ sodium | ||
Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2]. | |||
TNU1176 | 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite | ||
2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite; Nucleoside Derivative - Fluoro-modified nucleoside. | |||
TNU1558 | 2’-Deoxy-2’-fluoro-ara-uridine | ||
2'-Deoxy-2'-fluoro-ara-uridine is a Nucleoside Derivative - 2'-Modified nucleoside, Fluoro-modified nucleoside, N-Methylated/ alkylated nucleoside. | |||
TNU1422 | 2'-F-2'-ara-N2-ibu-dG Phosphoramidite | ||
2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a Nucleoside Phosphoramidite. | |||
T38730 | Ara-F-NAD+ | ||
Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM. | |||
TNU0493 | 2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine | ||
2'-Deoxy-2'-fluoro-6-S-Methyl-6-thio-ara-guanosine is a Nucleoside Derivative - 6-Modified purine nucleoside; Thio-nucleoside; Fluoro-modified nucleoside. | |||
T13907 | Sulfo-ara-F-NMN | CZ-48 | Others |
Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NM... |