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Lodenosine

Catalog No. T19688 CAS 110143-10-7

Synonyms: FddA, 3'-dideoxyarabinosyladenine, Fddl, 2'-F-dd-ara-A, 2'-Fluoro-2', DDG-1

Lodenosine is an inhibitor of RNA-directed DNA polymerase, and potentially for the treatment of HIV.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Lodenosine, CAS 110143-10-7

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Lodenosine is an inhibitor of RNA-directed DNA polymerase, and potentially for the treatment of HIV.

Synonyms	FddA, 3'-dideoxyarabinosyladenine, Fddl, 2'-F-dd-ara-A, 2'-Fluoro-2', DDG-1
Molecular Weight	253.23
Formula	C10H12FN5O2
CAS No.	110143-10-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Bei N, Li G, Meng Z, Weng Y, Zavala M, Molina LT. Impacts of using an ensemble Kalman filter on air quality simulations along the California-Mexico border region during Cal-Mex 2010 field campaign. Sci Total Environ. 2014 Nov 15;499:141-53. doi: 10.1016/j.scitotenv.2014.07.121. PubMed PMID: 25181046. 2. Rahman Z, MacFalls H, Jiang K, Chan KF, Kelly K, Tournas J, Stumpp OF, Bedi V, Zachary C. Fractional deep dermal ablation induces tissue tightening. Lasers Surg Med. 2009 Feb;41(2):78-86. doi: 10.1002/lsm.20715. PubMed PMID: 19226572. 3. Katayama S, Takamatsu S, Hirose N, Izawa K, Maruyama T. Synthesis of fluorinated nucleosides. Curr Protoc Nucleic Acid Chem. 2006 Jul;Chapter 1:Unit 1.12. doi: 10.1002/0471142700.nc0112s25. PubMed PMID: 18428944. 4. Saravanan G, Ozeki S. Magnetic field control of electron tunneling pathways in the monolayer of (ferrocenylmethyl)dodecyldimethylammonium bromide on a gold electrode. J Phys Chem B. 2008 Jan 10;112(1):3-6. PubMed PMID: 18076154.

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molecular Weight Calculator

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Lodenosine 110143-10-7 DDG 1 FddA 3'-dideoxyarabinosyladenine Fddl DDG1 2'-F-dd-ara-A 2'-Fluoro-2' DDG-1 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.