acetaminophen — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0065	Acetaminophen	4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol	COX , Endogenous Metabolite , Histone Acetyltransferase
	Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.		COX , Endogenous Metabolite , Histone Acetyltransferase
TN7063	N-Acetaminophen	NSC 403155,N-Acetyldemecolcine,N-Methylcolchicine,N-Acetylcolchamine	Others
	N-Acetaminophen (N-Methylcolchicine) is a methylated form of Colchicine.		Others
T19175	Acetaminophen metabolite 3-hydroxy-acetaminophen	3-Hydroxyacetaminophen	Others
	3-hydroxy-acetaminophen is a metabolite of Acetaminophen. Acetaminophen is a pain medicine.		Others
T20215	Acetaminophen mercapturate
	Paracetamol Mercapturate is a metabolite of Acetaminophen. It can also be used in the biological study of urinary antihypertensive drugs.
T36826	Acetaminophen Glucuronide (sodium salt)
	Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen . It is formed via glucuronidation of acetaminophen by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A6, UGT1A...
T38206	3-Cysteinylacetaminophen (trifluoroacetate salt)	APAP-Cys,3-(cysteine-S-yl)acetaminophen,3-Cysteinylacetaminophen (trifluoroacetate salt)
	3-Cysteinylacetaminophen is an acetaminophen-protein adduct formed during the metabolism of acetaminophen.[1],[2] 3-Cysteinylacetaminophen has been found in isolated human serum following therapeutic and supratherapeutic...
T29415	3-Methylacetaminophen
	3-Methylacetaminophen is a bioactive chemical.
T4545	Propacetamol Hydrochloride	Propacetamol HCL	Others
	Propacetamol Hydrochloride (Propacetamol HCL) is a prodrug of paracetamol (acetaminophen) with improved water solubility. Propacetamol Hydrochloride is an analgesic drug delivered by IV when the oral application of NSAID...		Others
T0914	Metacetamol	3-Acetamidophenol	Others
	Metacetamol (3-Acetamidophenol) is a derivative of acetaminophen, a non-toxic regional isomer of acetaminophen. It is an over-the-counter analgesic and antipyretic and is also used as an organic synthesis intermediate.		Others
T3913	Saikosaponin D		Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
	Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.		Estrogen Receptor/ERR , NF-κB , Antibacterial , STAT
T7280	CAY10594		Phospholipase
	CAY10594 is a potent phospholipase D2(PLD2) inhibitor. CAY10594 ameliorates acetaminophen-induced acute liver injury by regulating the phosphorylated-GSK-3β/JNK axis.		Phospholipase
TF0106	Cholesteryl Hemisuccinate Tris Salt		Apoptosis
	Cholesteryl Hemisuccinate Tris Salt is an acidic cholesteryl ester with hepatoprotective and anticancer activity.Cholesteryl hemisuccinate is a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing C...		Apoptosis
T67509	Cholesteryl Hemisuccinate	Cholesterol hydrogen succinate	Apoptosis , DNA/RNA Synthesis , Topoisomerase
	Cholesteryl Hemisuccinate (Cholesterol hydrogen succinate) is a highly soluble cholesterol analogue often used in polar solutions for its hepatoprotective, anticancer and tumour growth inhibiting properties. Cholesteryl ...		Apoptosis , DNA/RNA Synthesis , Topoisomerase
T9948	NecroX-7	LC-280126,LC28-0126,LC28 0126	NADPH-oxidase
	NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing ...		NADPH-oxidase
T4322	2-Hydroxybutyric acid	α-Hydroxybutyric acid	Endogenous Metabolite
	2-Hydroxybutyric acid (α-Hydroxybutyric acid) is a product of protein metabolism and a biomarker for type 2 diabetes and pre-eclampsia.		Endogenous Metabolite
T33881	Paracetamol mercapturate
	Paracetamol mercapturate is a deuterated metabolite of acetaminophen.
T10143	4-Hydroxyacetophenone oxime		Others
	4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent COX-2 and hepatic NAT2 inhibitor and used antipyretic and analgesic drug.		Others
T10135	4-Acetamidophenyl acetate		Others
	4-Acetamidophenyl acetate is an impurity of Acetaminophen. Acetaminophen is a selective COX-2 inhibitor (IC50: 25.8 μM) and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.		Others
T38312	L-Cysteine-glutathione disulfide
	L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to p...
T76364	Ac-Leu-Leu-Norleucinol
	Ac-Leu-Leu-Norleucinol (ALLN), a calpain inhibitor, is employed in the research of Acetaminophen-induced acute liver damage. It effectively reduces levels of glutamic-oxalacetic transaminase (ALT) and glutamic-pyruvic tr...