?plaque — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15108	DG-041		Prostaglandin Receptor
	DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per...		Prostaglandin Receptor
T0328	Hexetidine	NSC-17764	Antibacterial , Antifungal
	Hexetidine (NSC-17764) is a bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.		Antibacterial , Antifungal
T14369	AZD-0284		ROR
	AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].		ROR
T7657	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat	MOG (35-55)	Others
	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) is a truncated peptide derived from the human Myelin Oligodendrocyte Glycoprotein (MOG).		Others
TP2045	CH 275
	Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin r...
T68006	Orilotimod potassium	APO805K1
	Orilotimod potassium (APO805K1) can be used to study plaque psoriasis.
T17038	Tepilamide fumarate	XP-23829	Others
	Tepilamide fumarate (XP-23829) is an oral fumaric acid ester and is used in the research of moderate to severe chronic plaque psoriasis.		Others
T1147	Chlorhexidine dihydrochloride	Chlorhexidine hydrochloride,Chlorhexidine 2HCl,NSC-185	CAT , Cell wall , Antibacterial , Antibiotic , Antifection
	Chlorhexidine dihydrochloride (NSC-185) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.		CAT , Cell wall , Antibacterial , Antibiotic , Antifection
T37445	Etanercept		TNF
	Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β to the TNF receptors on cell surfaces, thereby rendering TN...		TNF
T1000L	Chlorhexidine diacetate	Hibitane diacetate,Chlorhexidine Acetate,Bactigras	CAT , Antibacterial , Antibiotic , Antifection
	Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.		CAT , Antibacterial , Antibiotic , Antifection
T0305	Erythrosine B	Erythrosine I,Erythrosin extra bluish,Erythrosin B	Others
	Erythrosine B (Erythrosine I) , a tetraiodofluorescein, is served as a red coloring in some foods (cherries, fish), as a disclosure of dental plaque, and as a stain of some cell types. Its structural was similar to thyro...		Others
T0578	Erythrosin B	Iodeosin,Tetraiodofluorescein	Others
	Erythrosin B (Iodeosin) , a tetraiodofluorescein, is used as a red coloring in some foods (cherries, fish), as a stain of some cell types, and as a disclosure of DENTAL PLAQUE. Its molecular structure is similar to THYRO...		Others
T77170	Siplizumab	MEDI-507	Others
	Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody targeting CD2. Siplizumab selectively depletes effector memory T cells and promotes relative expansion of alloreactive regulatory T cells in vitro. Siplizumab...		Others
T16094	MK-3328		Others
	MK-3328 has a high affinity for β-Amyloid (IC50:10.5 nM), and can be used as a candidate PET ligand for clinical assessment of β-amyloid plaque load. MK-3328 is a potential treatment for Alzheimer's disease.		Others
T9930	Secukinumab		IL Receptor
	Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for the treatment of moderate to severe plaque psoriasis.		IL Receptor
T64167	Ifebemtinib	IN-10018,BI-853520	FAK
	Ifebemtinib (BI-853520) is an orally active and potent inhibitor of adhesion plaque kinase (FAK) (IC50=1 nM) with anti-tumour activity that inhibits globule formation and in situ tumour growth in malignant pleural mesoth...		FAK
T76924	Efalizumab	Hu1124,HU 1124	Integrin
	Efalizumab, a novel potent regulator of T cells, is a humanized LFA-1 α subunit (CD11a) monoclonal antibody. Efalizumab has inhibitory effects on T cell activation, skin T cell transport, and T cell adhesion to keratinoc...		Integrin
T0900	Cetylpyridinium chloride monohydrate	Hexadecylpyridinium chloride monohydrate	Antibacterial , Antibiotic
	Cetylpyridinium chloride monohydrate (Hexadecylpyridinium chloride monohydrate) , a cationic quaternary ammonium compound, is used in certain classes of throat sprays, mouthwashes, lozenges, toothpaste, nasal sprays, and...		Antibacterial , Antibiotic
T5244	Aminomalonic acid	2-Aminopropanedioic Acid,Aminomalonate	Others , Endogenous Metabolite
	Aminomalonic acid (Aminomalonate) (Ama) was first detected in alkaline hydrolysates of proteins in 1984. Ama has been isolated from proteins of Escherichia coli and human atherosclerotic plaque. The presence of Ama has i...		Others , Endogenous Metabolite
T38105	Ixekizumab	LY2439821	IL Receptor , Interleukin
	Ixekizumab (LY2439821) is a humanized IgG4 monoclonal antibody that selectively binds and neutralizes interleukin IL-17A with a Kd value of <3 pM.Ixekizumab blocks the binding of IL-17A to IL-17RA but not to other IL-17 ...		IL Receptor , Interleukin