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Search Results for " 5-lipoxygenase "

20

Compounds

Cat No. Product Name Synonyms Targets
T10151 5-Lipoxygenase-In-1 Lipoxygenase
5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.
T8260 4',5-Dihydroxyflavone Lipoxygenase , Glucosidase
4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).
T8356 FPL 62064 Lipoxygenase , COX
FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase, respectively).
T5714 5-O-Demethylnobiletin 5-DEMETHYLNOBILETIN Leukotriene Receptor , Lipoxygenase
5-O-Demethylnobiletin (5-DEMETHYLNOBILETIN) is a natual product, has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecting the expression of COX-2.
T3S0153 Xanthatin Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr...
TN2330 Phenethyl ferulate Caffeic Acid 3-Methyl Phenethyl Ester Lipoxygenase , COX
Phenethyl ferulate (Caffeic Acid 3-Methyl Phenethyl Ester) has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane induced colon tumors. It shows inhibitory a...
T6S0413 Pectolinarigenin Pectolinaringenin Others , Lipoxygenase , COX
1. Pectolinarigenin (Pectolinaringenin) exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eicosanoid formation in ...
T3399 Psoralidin Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial
Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties.
T75122 5-Lipoxygenase-IN-3
5-Lipoxygenase-IN-3 (Compound 14), with an IC50 of less than 1 μM, serves as an inhibitor of 5-Lipoxygenase. This compound is utilized in the research of inflammatory diseases, cancer, stroke, and Alzheimer's disease [1]...
T16802 Lonapalene RS4317 Others
Lonapalene is a topically effective inhibitor of 5-lipoxygenase.
T61211 5-LOX-IN-1 Lipoxygenase
5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.
T12784 RWJ 63556 RWJ-63556 Lipoxygenase , COX
RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.
T22054 BW 755C Lipoxygenase
BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
T27244 Efletirizine UCB 28754,UCB-28754,UCB28754 Lipoxygenase , Histamine Receptor
Efletirizine (UCB-28754) is a histamine receptor antagonist with inhibitory effects on the enzyme 5-lipoxygenase (5-LO), and is useful in the topical treatment of allergic diseases.
T16817 S-2474 Lipoxygenase , COX
S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities and inhibits Abeta (25 - 35) and Abeta (1 - 40) induced cell death.
T16503 PF-4191834 PF-04191834 Lipoxygenase
PF-4191834 is a noniron chelating and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) with an IC50 of 229 nM. PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the ...
T25737 Linetastine TMK 688,TMK-688,TMK688 Lipoxygenase , LTR , Histamine Receptor
Linetastine (TMK-688) is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in studies of asthma, atherosclerosis, and peptic ulcers.
TN2068 Picrinine Lipoxygenase
Picrinine is an akuammiline alkaloid extracted from the leaves of Alstonia scholaris. It exhibits anti-inflammatory activity by inhibiting 5-lipoxygenase.
TN1255 3-O-Acetyl-11-hydroxy-beta-boswellic acid Lipoxygenase
3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).
T8950 CAY10698 Lipoxygenase
CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 µM).
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TargetMol