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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12597 | 5-HT2 antagonist 1 | 5-HT Receptor | |
5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity. | |||
T36949 | Niaprazine | 5-HT Receptor , Adrenergic Receptor , Histamine Receptor | |
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff... | |||
T15270 | Fananserin | RP 62203 | Dopamine Receptor , 5-HT Receptor |
Fananserin is an effective, selective and oral active antagonist of 5-HT2 (Ki = 0.37 nM for the rat 5-HT2A). Fananserin is an antagonist of human D4 receptor (Ki = 2.93 nM). | |||
T0137 | Mirtazapine | 6-Azamianserin,Org3770 | Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor |
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and h... | |||
T79804 | 5-HT2 agonist-1 | 5-HT Receptor | |
Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. The free base form of this compound is utilized in research pertaini... | |||
T14968 | Cinanserin hydrochloride | SQ 10643 | Influenza Virus , 5-HT Receptor |
Cinanserin hydrochloride (SQ 10643) is a high affinity antagonist of the 5-HT2 receptor (Ki: 41 nM) and a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. | |||
T1045 | Trimipramine maleate | Surmontil maleate | Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal... | |||
T4369 | SCH-23390 hydrochloride | R-(+)-SCH23390 hydrochloride | Potassium Channel , Dopamine Receptor , 5-HT Receptor |
SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM). | |||
T79805 | 5-HT2 agonist-1 free base | 5-HT Receptor | |
Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively. It is utilized in research pertaining to depression... | |||
T1567 | Olanzapine | LY170053 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR |
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness. | |||
T22904 | L-745870 trihydrochloride | L-745,870 trihydrochloride | Dopamine Receptor , Sigma receptor , 5-HT Receptor , Adrenergic Receptor |
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. | |||
T12865 | SCH-23390 maleate | R-(+)-SCH-23390 maleate | Potassium Channel , Dopamine Receptor , 5-HT Receptor |
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, respectively). | |||
T5389 | Volinanserin | M 100907,MDL100907 | 5-HT Receptor |
Volinanserin (MDL100907) (MDL 100907) is a potent and selective antagonist of the serotonin receptor 5-HT2 (Ki: 0.36 nM) and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 adrenergic and sigma recepto... | |||
T22029 | AL 34662 | 5-HT Receptor , Adrenergic Receptor | |
AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a low affinity α-1D adrenergic agonist, with an EC50 of 0.4 μM.... | |||
T23382 | Spiroxatrine | R 5188 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity and inhibitory effects on 5-HT1α, 5-HT1 β, 5-HT2, and dopamine receptors.Spiroxatrine may be used in the stu... | |||
T16759 | Ritanserin | R 55667 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor |
Ritanserin (R 55667) is a highly effective, relatively selective, long-acting antagonist of 5-HT2 receptor (IC50: 0.9 nM), less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2 receptors. | |||
T8702 | SKF-83566 | Dopamine Receptor , 5-HT Receptor , AChR | |
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM | |||
T21855 | AMI-193 | Espiramida,Spiramide | Dopamine Receptor , 5-HT Receptor |
AMI-193 (Spiramide) is an effective and selective antagonist of 5-HT2 and D2 receptor with Kis of 2, 3, 50, 2530, and 4300 nM for 5-HT2, D2 Receptor, 5-HT1A, D1 Receptor, and 5-HT1C Receptor. AMI-193 shows antipsychotic ... | |||
T22959 | M-Chlorophenylbiguanide hydrochloride | 1-(3-Chlorophenyl)biguanidehydrochloride | 5-HT Receptor |
5-HT3 receptor agonist | |||
T2599 | Pirenperone | 5-HT Receptor | |
Pirenperone is a putative 5-HT2 receptor antagonist with the central antiserotonergic and antidopaminergic action. |