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Search Results for " 5-ht1d "

20

Compounds

Cat No. Product Name Synonyms Targets
TQ0311 GSK163090 Dopamine Receptor , 5-HT Receptor
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
T8737 GR 125743 5-HT Receptor
GR 125743 is a novel antagonist of 5-HT1B/1D receptor.
T0203 Sumatriptan succinate GR 43175 5-HT Receptor
Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache.
T11326 Frovatriptan succinate hydrate Frovelan,Frova 5-HT Receptor
Frovatriptan succinate hydrate (Frova) is effective in treating the full spectrum of migraine including the associated symptoms of nausea, vomiting, photophobia, and phonophobia. Frovatriptan succinate hydrate can also b...
T6423 BRL-15572 dihydrochloride BRL 15573 dihydrochloride 5-HT Receptor
BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B recepto...
T2688 LY310762 LY310762 HCl 5-HT Receptor
LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM.
T11075 Donitriptan 5-HT Receptor
Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively.
T12861 SB-277011 SB-277011A Dopamine Receptor
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively.
T22808 GR 46611 5-HT Receptor
GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.
T22689 CP94253 hydrochloride CP 94253 hydrochloride Others , 5-HT Receptor
CP94253 hydrochloride (CP 94253 hydrochloride) is a potent, selective and centrally active agonist of 5-HT1B receptor with Ki of 2 nM. The Kis are 89, 49, 860, and 1600 nM for 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 receptors, ...
T6602 Naratriptan hydrochloride Naratriptan HCl,Amerge,Naramig,GR-85548A hydrochloride 5-HT Receptor
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydroc...
T5858 Sertindole Lu 23-174 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Autophagy
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively)
T34081 Piromelatine NEU-P-11,NEU-P 11,NEU-P11 P2X Receptor , 5-HT Receptor , MT Receptor , Sodium Channel , TRP/TRPV Channel
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibitory effects on P2X3, TRPV1, and Nav1.7 channels, and can be ...
T23265 RS 67333 hydrochloride RS 67333 (hydrochloride),RS 67333 HCl 5-HT Receptor
RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, inclu...
T4118 SB 271046 hydrochloride SB 271046A 5-HT Receptor
SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and ...
T1092 Zolmitriptan 311C90,BW-311C90 5-HT Receptor
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and...
T37816 SB 243213
SB 243213 is an orally active, selective and high-affinity 5-HT2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor. SB 243213 shows greater than a 100-fold selectivity over a wide range o...
T16556 PNU-142633 5-HT Receptor
PNU-142633 has anti-migraine efficacy. PNU-142633 is a high affinity and selective 5-HT1D receptor agonist (Kis of 6 nM and > 18 000 nM for human 5-HT1D receptor and human 5-HT1B receptor, respectively).
T23405 Sumatriptan Others
Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B, and 5-HT1A.
T26598 Alniditan dihydrochloride
Alniditan dihydrochloride is a potent 5-HT1D agonist and migraine-abortive agent.
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