5-fu — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8182L	Guan-fu base A hydrochloride(1394-48-5 free base)		P450
	Guan-fu base A hydrochloride is an antiarrhythmic alkaloid was isolated from Aconitum coreanum. Guanfu base A is hydrochloride a CYP2D6 inhibitor of human, monkey, and dog isoforms.		P450
T0984	5-Fluorouracil	5-FU,Fluorouracil,NSC 19893,5-Fluoracil	Apoptosis , Nucleoside Antimetabolite/Analog , HIV Protease , DNA/RNA Synthesis , Endogenous Metabolite
	5-Fluorouracil (5-FU) is a uracil analog, an inhibitor of DNA synthesis. 5-Fluorouracil has antitumor activity and affects pyrimidine synthesis through inhibition of thymidylate synthase. 5-Fluorouracil causes apoptosis ...
T7614	Eniluracil	GW776C85,5-Ethynyluracil	Others
	Eniluracil (GW776C85) is an orally activedihydropyrimidine dehydrogenase (DPD) inhibitor,increases the oral bioavailability of 5-FU to 100%, facilitating uniform absorption and predictable toxicity.		Others
T2911	Stevioside		TLR
	A natural, noncaloric sweetener with a potency 300 times more than that of regular sucrose. Exhibits transepithelial p-aminohippurate transport via organic anion transport system interference.		TLR
T33762	Fosifloxuridine nafalbenamide	NUC-3373,NUC3373,NUC 3373	DNA/RNA Synthesis
	Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher c...		DNA/RNA Synthesis
T10013	1-Acetyl-3-o-toluyl-5-fluorouracil	A-OT-Fu	Others
	1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.		Others
TNU1475	5’-O-DMTr-2’-FU-methyl phosphonamidite
	5’-O-DMTr-2’-FU-methyl phosphonamidite is a useful organic compound for research related to life sciences and the catalog number is TNU1475.
T1600	Doxifluridine	Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine	Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by...		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
T4374	Edoxudine	Aedurid,EUDR,Epoxudine	Antiviral , Antibacterial
	Edoxudine (Epoxudine), an antiviral drug, is an analogue of thymidine and shows effectiveness against the herpes simplex virus. Edoxudine is used as a 5-fluorouracil (FU) modulator. Edoxudine may be used to enhance the t...		Antiviral , Antibacterial
T1408	Capecitabine	Xeloda,Capecitibine,Capiibine,RO 09-1978	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	Capecitabine (Capecitibine) is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moie...
T4720	6-Hydroxypyridin-2(1H)-one hydrochloride	2,6-Dihydroxypyridine hydrochloride	Others , Endogenous Metabolite
	6-Hydroxypyridin-2(1H)-one hydrochloride (2,6-Dihydroxypyridine hydrochloride) is used as a reagent to synthesize uridine phosphorylase inhibitors that increase Uridine (Urd) (U829910) levels. Uridine is a promising bioc...		Others , Endogenous Metabolite
T21327	Uridine triacetate	RG 2133 triacetate,PN-401,Tri-O-acetyluridine,PN401,RG 2133,RG-2133,PN 401,RG2133,RG2133 triacetate	Others
	Uridine triacetate (RG 2133 triacetate) (Tri-O-acetyl uridine), an orally active prodrug of uridine, is efficiently absorbed in the gut and swiftly deacetylated in the circulation to release free uridine. It is utilized ...		Others
T5987	Potassium oxonate	Oxonic Acid (potassium salt),Potassium otastat,Potassium azaorotate	Others
	Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats.		Others
T4S1551	Cinnamaldehyde	Cinnamic Aldehyde	HIF
	1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express...		HIF
T72991	Bis-Pro-5FU
	Bis-Pro-5FU, a precursor to 5-Fluorouracil (5-FU), enhances the oral bioavailability and safety profile of 5-FU chemotherapy treatments. 5-FU itself is an antineoplastic antimetabolite extensively utilized in the researc...
T33686	Nitrocaphane	AT 1258,AT-1258,AT1258
	Nitrocaphane, in combination with 5-FU (fluorouracil), chemotherapy is considered as a protocol of choice in the treatment of malignant trophoblastic tumor.
T36870	5,6-dihydro-5-Fluorouracil	5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione	Others
	5,6-dihydro-5-Fluorouracil (5-FUH2) is an inactive metabolite of 5-FU and can be used for the study of organismal metabolism.		Others
T63868	α5β1 integrin agonist-1
	α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.
T40932	Benzylacyclouridine	5-Benzylacyclouridine,BAU
	Benzylacyclouridine (BAU) is a powerful and selective inhibitor of uridine phosphorylase, the initial enzyme involved in uridine catabolism. Additionally, it can regulate the cytotoxic adverse effects of 5-fluorouracil (...
TP2108	TAPI 2
	ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes.