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Potassium oxonate

Catalog No. T5987 CAS 2207-75-2

Synonyms: Oxonic Acid (potassium salt), Potassium otastat, Potassium azaorotate

Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats.

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Potassium oxonate, CAS 2207-75-2

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500 mg	In stock	$ 45.00

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Purity: 98.55%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that prevents metabolism and excretion of uric acid and induces embryotoxicity and nephrotoxicity in rats.
In vivo	Oxonic Acid? is a component of S-1, a mixture containing a prodrug of the antitumor agent 5-fluorouracil, that suppresses the gastrointestinal toxicity of 5-FU without inhibiting its antitumor activity in rats[1].Formulations containing oxonic acid have been used to treat gastric, pancreatic, lung, head, neck, and breast carcinomas[2].

Synonyms	Oxonic Acid (potassium salt), Potassium otastat, Potassium azaorotate
Molecular Weight	195.17
Formula	C4H2KN3O4
CAS No.	2207-75-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 9.09 mg/mL (46.57 mM), Sonication is recommended.

References and Literature

1. Yoshisue K, Masuda H, Matsushima E,et al.Tissue distribution and biotransformation of potassium oxonate after oral administration of a novel antitumor agent (drug combination of tegafur, 5-chloro-2,4-dihydroxypyridine, and potassium oxonate) to rats[J].Drug Metab Dispos. 2000 Oct;28(10):1162-7. 2. Chhetri P . Current Development of, Anti-Cancer Drug S-1[J]. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compounds Library Max Bioactive Compound Library NO PAINS Compound Library

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Keywords

Potassium oxonate 2207-75-2 Others Oxonic Acid (potassium salt) inhibit Potassium otastat Oxonic Acid Inhibitor Potassium azaorotate inhibitor

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