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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19613 | (3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol | Others | |
(3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol is a steroid-based allylic alcohol. | |||
T7358 | YK11 | Androgen Receptor | |
YK11 is an androgen receptor partial agonist that activates androgen receptor transcriptional activity in HEK293 cells overexpressing androgen receptors when used at a concentration of 0.1 μM, with osteogenic activity. | |||
TN3910 | Ecdysone | Apoptosis , ATPase , Glucocorticoid Receptor , Potassium Channel , Sodium Channel , Endogenous Metabolite , Autophagy | |
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signaling through Ecdysone receptor isoform B1 is required cell a... | |||
T36397 | TAN 420E | ||
TAN 420E is a bacterial metabolite originally isolated from Streptomyces. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 1.3 μM) and reduces thiobarbituric acid reactive substances (TBAR... | |||
T2881 | Crustecdysone | Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,Hydroxyecdysone | Others , Caspase , Endogenous Metabolite , Autophagy |
Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects. | |||
TN2114 | Pseudoginsenoside Rh2 | ERK , Raf , p53 | |
Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for excessive activation of the Ras/Raf/ERK/p53 pathway. (20Z) -Pseudoginsenoside Rh2 and (20E)-Pseudoginsenosid... | |||
T61339 | LDHA/PDKs-IN-1 | ||
LDHA/PDKs-IN-1 (compound 20e) is a highly effective dual inhibitor of PDKs and LDHA, displaying IC50 values of 0.8 μM and 0.15 μM, respectively. It significantly suppresses A549 cell proliferation (EC50 = 13.2 μM), reduc... |