2'-fluoro-2' — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9727	2'-Fluoro-2'-Deoxyadenosine		Nucleoside Antimetabolite/Analog
	2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors ex...		Nucleoside Antimetabolite/Analog
T36752	Dmt-2'fluoro-da(bz) amidite		DNA/RNA Synthesis
	Dmt-2'fluoro-da(bz) amidite is a 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotide with high affinity and specificity for RNA targets.Dmt-2'fluoro-da(bz) amidite is also an intermediate in the synthesis of 5'-DMT-3'-ph...		DNA/RNA Synthesis
T38958	DMT-2′Fluoro-dU Phosphoramidite	2'-F-dU Phosphoramidite	Nucleoside Antimetabolite/Analog
	DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.		Nucleoside Antimetabolite/Analog
T7718	5-Fluoro-2'-deoxycytidine	FdCyd,2'-DEOXY-5-FLUOROCYTIDINE	DNA Methyltransferase
	5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .		DNA Methyltransferase
TNU0187	2',5-Difluoro-2'-deoxy-1-arabinosyluracil	2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine	Nucleoside Antimetabolite/Analog
	2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) is a urinary pyrimidine nucleoside analogue with potential antiepileptic and antihypertensive activity, which can be used to study an...		Nucleoside Antimetabolite/Analog
T19101	2'-Fluorothymidine	2'-Deoxy-2'-fluoro-5-Methyluridine,2'-Deoxy-2'-fluoro-5-Methyluridine	Others
	2'-Fluorothymidine(2'-Deoxy-2'-fluoro-5-Methyluridine) belongs to the thymidine (TdR) and methyluridine isozymes and is a highly selective substrate for thymidine kinase type 2 (TK2).		Others
TNU0159	FMAU	2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine	Apoptosis
	FMAU (2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine) is a thymine nucleoside analog with insertional activity on replicating DNA.FMAU can be used to label cells and track DNA synthesis.		Apoptosis
T9900	5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine 2',3'-diacetate		Others
	5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine 2',3'-diacetate is an intermediate in the synthesis of capecitabine.		Others
T3580	FIPI	5-Fluoro-2-indolyl deschlorohalopemide	Phospholipase , Autophagy
	FIPI (5-Fluoro-2-indolyl deschlorohalopemide) is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell s...		Phospholipase , Autophagy
T9832	(Rac)-EC5026	Urea, N-[3-fluoro-4-(trifluoromethoxy)phenyl]-N'-[1-(2-methyl-1-oxobutyl)-4-piperidinyl]-	Epoxide Hydrolase
	(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) with Ki of 0.06 nM. (Rac)-EC5026 can be used for the research of Parkinson's disease and dementia with Lewy Bodies (DLB) ...		Epoxide Hydrolase
T8741	MitoBloCK-10	3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m	Others
	MitoBloCK-10 (3-fluoro-N'-[(E)-(5-nitrothiophen-2-yl)m) inhibits Tim44 binding to the precursor and to Hsp70.MitoBloCK-10 is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity...		Others
T2117	PSI-6206	2'-deoxy-2'-fluoro-2'-C-methyluridine,RO 2433,GS-331007	HCV Protease
	PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.		HCV Protease
T9421	5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid		Others
	5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is a sunitinib impurity.		Others
T35682	2-deoxy-2-fluoro-D-Glucose
	2-deoxy-2-fluoro-D-Glucose (2-FG) is a derivative of glucose with anticancer activity.1It inhibits the growth of 143B osteosarcoma cells grown under normoxic and hypoxic conditions when used at concentrations of 6 and 24...
T8871	C/EBPα inducer 1	4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-	Others
	C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via upregulation of C/EBP.		Others
T38089	2F-Peracetyl-Fucose	1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos	Others
	2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) is a potent fucosyltransferase (FUT) inhibitor that inhibits salivary acidification and fucosylation in an in vitro inflammatory model.		Others
T9645	CU-115	N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide	TLR
	CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-α and IL-1β activated by R-848 in THP-1 cells.		TLR
T29348	2-Fluoro-ADP
	2-Fluoro-ADP is a bioactive chemical.
T38372	2-Fluoro-4-iodo benzonitrile
	2-Fluoro-4-iodo benzonitrile is a building block.1,2It has been used in the synthesis ofL. infantumtrypanothione reductase (Li-TryR) dimerization and oxidoreductase activity inhibitors.12-Fluoro-4-iodo benzonitrile has a...
T9585	GNE-9815	3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide	Raf
	GNE-9815 (3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide) is a high kinase-selective inhibitor of RAF and targets KRAS-mutant cancers through combina...		Raf