The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.The PROSITE pattern of this superfamily is located in a beta sheet in the central section of the protein that is conserved across all members.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-02233 | TRAIL/TNFSF10 Protein, Human, Recombinant
TRAIL/TNFSF10 Protein, Human, Recombinant
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Human | E. coli |
TRAIL/TNFSF10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P50591.... | |||
TMPJ-00064 | OX40L/TNFSF4 Protein, Human, Recombinant (His)
OX40L/TNFSF4 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells,... | |||
TMPJ-00075 | CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular ... | |||
TMPJ-00124 | TNF alpha Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His)
|
Human | E. coli |
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16 KDa and t... | |||
TMPJ-00125 | TNF alpha Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His)
|
Human | E. coli |
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and t... | |||
TMPJ-00138 | 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 K... | |||
TMPJ-00150 | CD40 Ligand Protein, Human, Recombinant (Mammalian)
CD40 Ligand Protein, Human, Recombinant (Mammalian)
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Human | HEK293 Cells |
CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number ... | |||
TMPJ-00151 | CD40 Ligand Protein, Human, Recombinant
CD40 Ligand Protein, Human, Recombinant
|
Human | E. coli |
CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965. | |||
TMPJ-00152 | CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is ... | |||
TMPJ-00153 | CD40 Ligand Protein, Human, Recombinant (His & Flag)
CD40 Ligand Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa an... | |||
TMPJ-00177 | BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
|
Human | HEK293 Cells |
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytoki... | |||
TMPJ-00178 | BAFF/TNFSF13B Protein, Human, Recombinant (His)
BAFF/TNFSF13B Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
BAFF/TNFSF13B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 22 KDa and the accessi... | |||
TMPJ-00432 | GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cy... | |||
TMPJ-00456 | APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthes... | |||
TMPJ-00623 | BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)
BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)
|
Rhesus | HEK293 Cells |
TNFSF13B is also known as B-cell activating factor (BAFF), BLyS and TNLG7A, is a member of TNF ligand superfamily. TNFSF/TNFRSF members function as key molecules... | |||
TMPJ-00920 | CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
|
Mouse | HEK293 Cells |
CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino ... | |||
TMPJ-01441 | OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and... | |||
TMPK-00053 | GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
|
Human | HEK293 Cells |
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, pro... | |||
TMPK-00054 | GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
|
Human | HEK293 Cells |
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, pro... | |||
TMPK-00078 | CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
|
Human | HEK293 Cells |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... |