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Tumor Necrosis Factor family, TNFs

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers. Members of this superfamily can be released from the cell membrane by extracellular proteolytic cleavage and function as a cytokine. These proteins are expressed predominantly by immune cells and they regulate diverse cell functions, including immune response and inflammation, but also proliferation, differentiation, apoptosis and embryogenesis. The superfamily contains 19 members that bind to 29 members of TNF receptor superfamily. The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.The PROSITE pattern of this superfamily is located in a beta sheet in the central section of the protein that is conserved across all members.

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Species
Canine (4)
Cynomolgus (19)
Ferret (2)
Human (70)
Mouse (30)
Rabbit (1)
Rat (9)
Rhesus (5)
Expression System
Baculovirus Insect Cells (4)
E. coli (23)
HEK293 Cells (107)
P. pastoris (Yeast) (3)
Tag
Avi (4)
C-6xHis (3)
C-His (4)
C-His-Avi (2)
C-hFc (2)
C-mFc (1)
Fc (3)
His (4)
N-10xHis (1)
N-6xHis (5)
N-6xHis-Avi (1)
N-6xHis-Flag (3)
N-8xHis (1)
N-Avi-Fc (1)
N-Flag (4)
N-Flag-His (1)
N-His (16)
N-His-Avi (7)
N-His-Flag (11)
N-hFc (20)
N-mFc (8)
N-monomeric hFc (2)
N-rFc (6)
Tag Free (24)
hFc (11)
Cat No. product name / Synonyms Species Expression System
TMPY-02233 TRAIL/TNFSF10 Protein, Human, Recombinant
TRAIL/TNFSF10 Protein, Human, Recombinant
Human E. coli
TRAIL/TNFSF10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P50591....
TMPJ-00064 OX40L/TNFSF4 Protein, Human, Recombinant (His)
OX40L/TNFSF4 Protein, Human, Recombinant (His)
Human HEK293 Cells
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells,...
TMPJ-00075 CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular ...
TMPJ-00124 TNF alpha Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His)
Human E. coli
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16 KDa and t...
TMPJ-00125 TNF alpha Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His)
Human E. coli
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and t...
TMPJ-00138 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
Human HEK293 Cells
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 K...
TMPJ-00150 CD40 Ligand Protein, Human, Recombinant (Mammalian)
CD40 Ligand Protein, Human, Recombinant (Mammalian)
Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number ...
TMPJ-00151 CD40 Ligand Protein, Human, Recombinant
CD40 Ligand Protein, Human, Recombinant
Human E. coli
CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
TMPJ-00152 CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is ...
TMPJ-00153 CD40 Ligand Protein, Human, Recombinant (His & Flag)
CD40 Ligand Protein, Human, Recombinant (His & Flag)
Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa an...
TMPJ-00177 BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
Human HEK293 Cells
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytoki...
TMPJ-00178 BAFF/TNFSF13B Protein, Human, Recombinant (His)
BAFF/TNFSF13B Protein, Human, Recombinant (His)
Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 22 KDa and the accessi...
TMPJ-00432 GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cy...
TMPJ-00456 APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
Mouse HEK293 Cells
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthes...
TMPJ-00623 BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)
BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)
Rhesus HEK293 Cells
TNFSF13B is also known as B-cell activating factor (BAFF), BLyS and TNLG7A, is a member of TNF ligand superfamily. TNFSF/TNFRSF members function as key molecules...
TMPJ-00920 CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
Mouse HEK293 Cells
CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino ...
TMPJ-01441 OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and...
TMPK-00053 GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
Human HEK293 Cells
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, pro...
TMPK-00054 GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
Human HEK293 Cells
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, pro...
TMPK-00078 CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
Human HEK293 Cells
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
TRAIL/TNFSF10 Protein, Human, Recombinant
TMPY-02233
TRAIL/TNFSF10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P50591....
OX40L/TNFSF4 Protein, Human, Recombinant (His)
TMPJ-00064
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein.OX40L is expressed on the surface of activated B cells,...
CD27 Ligand/CD70 Protein, Mouse, Recombinant (His)
TMPJ-00075
CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular ...
TNF alpha Protein, Human, Recombinant (aa 77-233, His)
TMPJ-00124
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16 KDa and t...
TNF alpha Protein, Human, Recombinant (aa 57-233, His)
TMPJ-00125
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and t...
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
TMPJ-00138
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 K...
CD40 Ligand Protein, Human, Recombinant (Mammalian)
TMPJ-00150
CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number ...
CD40 Ligand Protein, Human, Recombinant
TMPJ-00151
CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00152
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is ...
CD40 Ligand Protein, Human, Recombinant (His & Flag)
TMPJ-00153
CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa an...
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated
TMPJ-00177
B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytoki...
BAFF/TNFSF13B Protein, Human, Recombinant (His)
TMPJ-00178
BAFF/TNFSF13B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 22 KDa and the accessi...
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
TMPJ-00432
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cy...
APRIL/TNFSF13 Protein, Mouse, Recombinant (hFc)
TMPJ-00456
Tumor necrosis factor ligand superfamily member 13 belongs to the tumor necrosis factor family. It is also known as APRIL, TALL2, TRDL1, and CD256. It is synthes...
BAFF/TNFSF13B Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00623
TNFSF13B is also known as B-cell activating factor (BAFF), BLyS and TNLG7A, is a member of TNF ligand superfamily. TNFSF/TNFRSF members function as key molecules...
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
TMPJ-00920
CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino ...
OX40L/TNFSF4 Protein, Cynomolgus, Recombinant (His)
TMPJ-01441
Tumor necrosis factor ligand superfamily member 4(TNFSF4/OX40L) is a single-pass type II membrane protein. OX40L is expressed by DCs, macrophages and B cells and...
GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
TMPK-00053
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, pro...
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
TMPK-00054
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, pro...
CD27 Ligand/CD70 Trimer Protein, Human, Recombinant (His), FITC-Labeled
TMPK-00078
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a...
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