Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C downstream pathway inhibition of 94%. VPC-70063 can be used for studies about anticancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 215.00 | |
10 mg | In stock | $ 297.00 | |
25 mg | In stock | $ 553.00 | |
50 mg | In stock | $ 789.00 | |
100 mg | In stock | $ 1,080.00 | |
500 mg | In stock | $ 2,180.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 232.00 |
Description | VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C downstream pathway inhibition of 94%. VPC-70063 can be used for studies about anticancer. |
In vitro | VPC-70063 (6.25, 12.5, and 25 μM) causes apoptosis of LNCaP cells as indicated by cleavage of PARP. VPC-70063 (0-500 μM) disrupts the interaction of Myc-Max with DNA in a dose-dependent manner[1]. |
Synonyms | Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)- |
Molecular Weight | 378.34 |
Formula | C16H12F6N2S |
CAS No. | 13571-44-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (118.94 mM)
You can also refer to dose conversion for different animals. More
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VPC-70063 13571-44-3 Apoptosis Cell Cycle/Checkpoint Chromatin/Epigenetic DNA Damage/DNA Repair PARP c-Myc Anticancer LNCaP Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)- VPC 70063 inhibit Myc-Max UBE2C AR-V7 Myc VPC70063 Inhibitor poly ADP ribose polymerase inhibitor