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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9061 | EN4 | EN4 MYC inhibitor | c-Myc |
EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, an... | |||
TP1315 | C-Myc Peptide Trifluoroacetate | Others | |
c-Myc Peptide Trifluoroacetate is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein. c-Myc Peptide Trifluoroacetate participates in regulation of growth-related gene transcr... | |||
T3048 | 10058-F4 | c-Myc Inhibitor | c-Myc , Autophagy |
10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; induces cell-cycle arrest and apoptosis. | |||
TP2311 | C-MYC PEPTIDE EPITOPE TFA | Others | |
C-MYC PEPTIDE EPITOPE TFA, the product of the c-myc proto-oncogene, is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription in cell proliferation, cell differentiation and apoptosis. This pe... | |||
T39751 | MYC-IN-2 | ||
MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research. | |||
TN1892 | Lusianthridin | Others , c-Myc | |
Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signali... | |||
T72040 | C-Myc inhibitor 7 | ||
C-Myc Inhibitor 7, serving as both a c-Myc inhibitor and a multi-target protein degrader, effectively degrades proteins c-MYC, CK1α, GSPT1, and IKZF1/2/3 across various tumor cell types. It holds potential for research i... | |||
TP2179 | C-Myc tag Peptide | Others | |
c-Myc Peptide is a useful displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific. c-My... | |||
T3686 | 10074-G5 | c-Myc , Autophagy | |
10074-G5 is an inhibitor of c-Myc-Max dimerization. | |||
T4252 | ML327 | c-Myc , Autophagy | |
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT). | |||
T15665 | KJ Pyr 9 | c-Myc , Autophagy | |
KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay). | |||
T9628 | 10074-A4 | c-Myc | |
10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand. | |||
T12132 | MYCi361 | NUCC-0196361 | c-Myc |
MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM). | |||
T4367 | Mycro 3 | Mycro-3 | c-Myc , Autophagy |
Mycro 3 is potent and selective for c-Myc in whole cell assays. | |||
T12134 | MYCMI-6 | NSC354961 | Apoptosis , c-Myc |
MYCMI-6 (NSC-354961) is a potent and selective inhibitor of endogenous MYC:MAX protein interactions,reduces proliferation and induces massive apoptosis in tumor tissue from a MYC-driven xenograft tumor model without seve... | |||
T60019 | VPC-70063 | Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)- | Apoptosis , PARP , c-Myc |
VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C do... | |||
T21065 | Artemisitene | Others | |
Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisini... | |||
T9033 | BTYNB | MDK6620,BTYNB IMP1 Inhibitor | Others , c-Myc , NF-κB |
BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa ... | |||
T78055 | MYC-RIBOTAC | c-Myc | |
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered to a small molecule that recruits and activates RNase L1. Th... | |||
T10352 | APTO-253 | LOR-253,LT-253 | Apoptosis , c-Myc , KLF |
APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the K... |