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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $48 | In Stock | |
10 mg | $67 | In Stock | |
25 mg | $107 | In Stock | |
50 mg | $156 | In Stock | |
100 mg | $229 | In Stock | |
500 mg | $572 | In Stock |
Description | Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, inhibits cerebral angiotensin II-dependent and -independent AT1 receptor responses. |
In vitro | GSNO completely abolished the AngII-dependent AT1 receptor-mediated vasoconstriction of cerebral arteries. GSNO had no impact on responses to other vasoconstrictors sharing (phenylephrine, U46619) or not (5-HT) the same signalling pathway[1]. |
In vivo | Elevated blood pressure, proteinuria, and intrauterine growth restriction associated with PE were induced in Sprague-Dawley rats using L-NAME. These were partially reversed with the use of GSNO[3]. |
Alias | S-Nitrosoglutathione, SNOG, Glutathione thionitrite, GSNO |
Molecular Weight | 336.32 |
Formula | C10H16N4O7S |
Cas No. | 57564-91-7 |
Storage | store at low temperature,keep away from moisture|Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||
Solubility Information | DMSO: Soluble H2O: 20 mg/mL (59.47 mM) | ||||||||||
Solution Preparation Table | |||||||||||
H2O
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