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Kaempferol 3,7,4'-trimethyl ether

Catalog No. TN1817   CAS 15486-34-7
Synonyms: Kaempferol 3,7,4'-trimethylether

Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) shows selective cyctoxic activities against the nine tested cancer cell lines.

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Kaempferol 3,7,4'-trimethyl ether Chemical Structure
Kaempferol 3,7,4'-trimethyl ether, CAS 15486-34-7
Pack Size Availability Price/USD Quantity
1 mg In stock $ 122.00
5 mg In stock $ 297.00
10 mg In stock $ 526.00
25 mg In stock $ 838.00
50 mg In stock $ 1,130.00
100 mg In stock $ 1,520.00
1 mL * 10 mM (in DMSO) In stock $ 333.00
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Purity: 99.05%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) shows selective cyctoxic activities against the nine tested cancer cell lines.
In vitro The IC50 values below or around 30 μg/mL were recorded with A. arundinaceum extract against eight of the nine tested cancer cell lines. This extract displayed IC50 values below 40 μg/mL towards the nine tested cancer cell lines whilst A. polyanthum extract, Kaempferol 3,7,4'-trimethylether showed selective activities. Collateral sensitivity (hypersensitivity) was observed with A. arundinaceum extract towards leukemia CEM/ADR5000 cells and glioblastoma U87MG.ΔEGFR compared to their respective sensitive counterparts CEM/CEM and U87MG.[1]
Source
Synonyms Kaempferol 3,7,4'-trimethylether
Molecular Weight 328.32
Formula C18H16O6
CAS No. 15486-34-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 11 mg/ml (33.5 mM)

TargetMolReferences and Literature

1. Kuete V, Ango PY, et al. Cytotoxicity of four Aframomum species (A. arundinaceum, A. alboviolaceum, A. kayserianum and A. polyanthum) towards multi-factorial drug resistant cancer cell lines. BMC Complement Altern Med. 2014 Sep 19;14:340.

Related compound libraries

This product is contained In the following compound libraries:
Traditional Chinese Medicine Monomer Library Flavonoid Natural Product Library Natural Product Library Chinese Pharmacopoeia Natural Product Library Bioactive Compounds Library Max Anti-Cancer Compound Library Traditional Mongolian Medicine Compound Library Oxidation-Reduction Compound Library RO5 Drug-like Natural Product Library Natural Product Library for HTS

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Keywords

Kaempferol 3,7,4'-trimethyl ether 15486-34-7 Immunology/Inflammation NO Synthase Inhibitor inhibit Kaempferol 3,7,4'-trimethylether Kaempferol 3,7,4' trimethyl ether Kaempferol 3,7,4'trimethyl ether inhibitor

 

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