Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JNJ-61432059 is an oral active and selective negative modulator of TARP γ‑8 Selective AMPAR(pIC50: 9.7).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 139.00 | |
5 mg | In stock | $ 297.00 | |
10 mg | In stock | $ 497.00 | |
25 mg | In stock | $ 793.00 | |
50 mg | In stock | $ 1,130.00 | |
100 mg | In stock | $ 1,520.00 | |
500 mg | In stock | $ 2,970.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 327.00 |
Description | JNJ-61432059 is an oral active and selective negative modulator of TARP γ‑8 Selective AMPAR(pIC50: 9.7). |
Targets&IC50 | AMPAR:(pic50)9.7 |
In vivo | In mouse hippocampus, Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models. |
Molecular Weight | 443.47 |
Formula | C25H22FN5O2 |
CAS No. | 2035814-50-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 42.5 mg/mL (95.84 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JNJ-61432059 2035814-50-5 Membrane transporter/Ion channel Neuroscience iGluR JNJ 61432059 Inhibitor Ionotropic glutamate receptors JNJ61432059 inhibit inhibitor