keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase and Wnt signalling, producing cytotoxicity in chronic lymphocytic leukaemia cells and other tumour cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 31.00 | |
50 mg | In stock | $ 46.00 | |
100 mg | In stock | $ 78.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 32.00 |
Description | Ethacrynic acid (Edecrin) is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase and Wnt signalling, producing cytotoxicity in chronic lymphocytic leukaemia cells and other tumour cells. |
Synonyms | Edecrin, Etacrynic Acid, Hydromedin |
Molecular Weight | 303.14 |
Formula | C13H12Cl2O4 |
CAS No. | 58-54-8 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 30 mg/mL
DMSO: 30 mg/mL
You can also refer to dose conversion for different animals. More
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Ethacrynic acid 58-54-8 Membrane transporter/Ion channel Metabolism NF-Κb Others oxidation-reduction GST NF-κB Calcium Channel Nuclear factor-κB inhibit Ca channels GSTs Nuclear factor-kappaB Edecrin Gutathione S-transferase Ca2+ channels Inhibitor Etacrynic Acid Hydromedin Glutathione transferases inhibitor