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Search Results for " α2-adrenoceptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T12643 (R)-Terazosin Adrenergic Receptor
(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent antagonist of α1-adrenoceptor (α1a, α1b and α1d-adrenoceptor with Ki values of 6.51 nM, 1.01 nM and 1.97 nM, respectively).
T3158 Harmane Loturine,Harman,Aribine Adrenergic Receptor , Monoamine Oxidase , Imidazoline Receptor
Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.
T6579 Medetomidine hydrochloride MPV785,Medetomidine HCl,Domitor Adrenergic Receptor
Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.
T0137 Mirtazapine 6-Azamianserin,Org3770 Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and h...
T11015 Midaglizole hydrochloride (±)-DG5128,(±)-DG5128 hydrochloride,DG5128 hydrochloride,DG5128 Adrenergic Receptor
Midaglizole hydrochloride ((±)-DG5128) (DG5128) is a preferred α2-adrenoceptor antagonist. Midazolazole hydrochloride (DG5128) has an affinity for α2-adrenoceptor (pKi = 6.28) 7.4 times higher than that of α1-adrenocepto...
T21957 Guanabenz hydrochloride NE56490 Adrenergic Receptor
Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects.
T14490 Talipexole dihydrochloride Domnin,B-HT 920 dihydrochloride Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, ...
T21787L Azepexole hydrochloride 4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1) Adrenergic Receptor
Azepexole hydrochloride (4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)) is a potent α2-Adrenoceptor agonist with anaesthetic effects.
T23397 ST 91 Others , Adrenergic Receptor
ST-91 is an agonist of α2-adrenoceptor with a mixed α-adrenergic receptor type/subtype selection profile.
T4526 Piperoxan hydrochloride dl-Piperoxan hydrochloride,Benodaine hydrochloride Adrenergic Receptor
Piperoxan hydrochloride (Benodaine hydrochloride) is an α2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered.
T5105 1-(2-Pyridyl)piperazine NSC13778 Adrenergic Receptor
1-(2-Pyridyl)piperazine (NSC-13778) is a selective α2-adrenoceptor antagonists. 1-(2-Pyridyl)piperazine shows sympatholytic activity. 1-(2-Pyridyl)piperazine is also a metabolite of Azaperone.
T77565 Fluparoxan hydrochloride Adrenergic Receptor
Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental disorders and neurodegenerative diseases.
T9762 Upidosin SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739 Adrenergic Receptor
Upidosin (SB-216469) is a potential uroselective α1-adrenoceptor antagonist, α1a subtype Ki=0.34 nM, α1b subtype Ki=3.9 nM, α1d subtype Ki=1.5 nM, α2-adrenoceptor Ki=33.3 nM.
T6466 Dexmedetomidine hydrochloride Precedex,(+)-Medetomidine hydrochloride,(S)-Medetomidine hydrochloride,Dexmedetomidine HCl Adrenergic Receptor
Dexmedetomidine hydrochloride (Precedex) is an imidazole derivative that is an agonist of the adrenergic alpha-2 receptor. It is closely-related to MEDETOMIDINE, which is the racemic form of this compound.
TN7042 N-methyltyramine Adrenergic Receptor
N-methyltyramine is an alkaloid isolated from the leguminous plant Acacia grandiflora.It is an α2-adrenoceptor antagonist that regulates adrenergic receptors through enzymatic adrenergic synthesis.It is used in the study...
T1247 Clonidine hydrochloride Clonidine HCl,Catapres Adrenergic Receptor
Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.
T21911 Rilmenidine hemifumarate Rilmenidine (hemifumarate),S-3341 hemifumarate Apoptosis , Imidazoline Receptor
Rilmenidine hemifumarate (S-3341 hemifumarate) is a novel, orally active and selective I1 imidazoline receptor and α2-adrenoceptor agonist that induces autophagy, regulates the proliferation of leukaemia cells, stimulate...
T0115 Idazoxan hydrochloride RX 781094 Adrenergic Receptor , Imidazoline Receptor
Idazoxan hydrochloride (RX 781094) is a benzodioxane-linked imidazole. It has alpha-2 adrenoceptor antagonist activity.
TN1015 Meranzin Adrenergic Receptor , Immunology/Inflammation related
Meranzin, a bioactive compound derived from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS) and isolated from Murraya exotica L. leaves, targets the alpha 2-adrenoceptor and engages the AMPA-ERK1/2–BDNF si...
T2524 Dexmedetomidine Adrenergic Receptor
Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is by means of General Anesthesia.

Compounds

(R)-Terazosin
T12643
Synonym:
Target: Adrenergic Receptor
Harmane
T3158
Synonym: Loturine,Harman,Aribine
Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor
Medetomidine hydrochloride
T6579
Synonym: MPV785,Medetomidine HCl,Domitor
Target: Adrenergic Receptor
Mirtazapine
T0137
Synonym: 6-Azamianserin,Org3770
Target: Dopamine Receptor, 5-HT Receptor, Opioid Receptor, Adrenergic Receptor, Histamine Receptor
Midaglizole hydrochloride
T11015
Synonym: (±)-DG5128,(±)-DG5128 hydrochloride,DG5128 hydrochloride,DG5128
Target: Adrenergic Receptor
Guanabenz hydrochloride
T21957
Synonym: NE56490
Target: Adrenergic Receptor
Talipexole dihydrochloride
T14490
Synonym: Domnin,B-HT 920 dihydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Azepexole hydrochloride
T21787L
Synonym: 4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)
Target: Adrenergic Receptor
ST 91
T23397
Synonym:
Target: Others, Adrenergic Receptor
Piperoxan hydrochloride
T4526
Synonym: dl-Piperoxan hydrochloride,Benodaine hydrochloride
Target: Adrenergic Receptor
1-(2-Pyridyl)piperazine
T5105
Synonym: NSC13778
Target: Adrenergic Receptor
Fluparoxan hydrochloride
T77565
Synonym:
Target: Adrenergic Receptor
Upidosin
T9762
Synonym: SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739
Target: Adrenergic Receptor
Dexmedetomidine hydrochloride
T6466
Synonym: Precedex,(+)-Medetomidine hydrochloride,(S)-Medetomidine hydrochloride,Dexmedetomidine HCl
Target: Adrenergic Receptor
N-methyltyramine
TN7042
Synonym:
Target: Adrenergic Receptor
Clonidine hydrochloride
T1247
Synonym: Clonidine HCl,Catapres
Target: Adrenergic Receptor
Rilmenidine hemifumarate
T21911
Synonym: Rilmenidine (hemifumarate),S-3341 hemifumarate
Target: Apoptosis, Imidazoline Receptor
Idazoxan hydrochloride
T0115
Synonym: RX 781094
Target: Adrenergic Receptor, Imidazoline Receptor
Meranzin
TN1015
Synonym:
Target: Adrenergic Receptor, Immunology/Inflammation related
Dexmedetomidine
T2524
Synonym:
Target: Adrenergic Receptor
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TargetMol