Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent antagonist of α1-adrenoceptor (α1a, α1b and α1d-adrenoceptor with Ki values of 6.51 nM, 1.01 nM and 1.97 nM, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 83.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 288.00 | |
25 mg | In stock | $ 485.00 | |
50 mg | In stock | $ 693.00 | |
100 mg | In stock | $ 987.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 228.00 |
Description | (R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent antagonist of α1-adrenoceptor (α1a, α1b and α1d-adrenoceptor with Ki values of 6.51 nM, 1.01 nM and 1.97 nM, respectively). |
Targets&IC50 | α1D-adrenoceptor:1.97 nM (Ki), α1a-adrenoceptor:6.51 nM (Ki), α1b-adrenoceptor:1.01 nM (Ki) |
In vitro | (R)-Terazosin is low affinity for α2a, α2B and α2c-adrenoceptor(Ki of 3.85 μM, 0.33 μM and 0.37 μM, respectively). (R)-Terazosin may prove to be a useful probe in understanding the functional role of subtypes of adrenoceptors in various tissues. |
In vivo | (R)-Terazosin shows antagonism of at rat atrial α2B receptor (pEC30 : 5.69). (R)-Terazosin shows antagonism of at rat vas deferens α1A and α2A receptor (pA2 of 7.5 and 5.31, respectively). |
Molecular Weight | 387.43 |
Formula | C19H25N5O4 |
CAS No. | 109351-34-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 75 mg/mL (193.58 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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(R)-Terazosin 109351-34-0 GPCR/G Protein Neuroscience Adrenergic Receptor Terazosin α1-adrenoceptor affinity inhibit subtypes prove (R)Terazosin Inhibitor (R) Terazosin Low α2-adrenoceptor Beta Receptor inhibitor