stimuli — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14767	BP 897 hydrochloride		Dopamine Receptor
	BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors ...		Dopamine Receptor
T9100	BP 897	2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-	Dopamine Receptor
	BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 ...		Dopamine Receptor
T2P2870	Damascenone	trans-damascenone,Beta-Damascenone	Others , NF-κB , Endogenous Metabolite
	Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.		Others , NF-κB , Endogenous Metabolite
T21380	Pravadoline	WIN 48098-6,WIN48098-6,WIN-48098-6	Cannabinoid Receptor
	Pravadoline (WIN48098-6) is a cannabinoid receptor agonist. Pravadoline inhibited the PGs synthesis in mouse brain and displayed antinociceptive activity in rodents subjected to a variety of thermal, chemical, and mechan...		Cannabinoid Receptor
TN3460	Asebogenin		Antifungal
	Asebogenin is a compound fractionated from Salvia miltiorrhiza with antifungal activity, inhibition of GPVI-induced platelet reactions, and inhibition of NET formation induced by pro-inflammatory stimuli.		Antifungal
T29968	AMG-0347	UNII-CD7L9290QR	TRP/TRPV Channel
	AMG-0347 (UNII-CD7L9290QR) is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neurons and involved in the detection of pain and environmental s...		TRP/TRPV Channel
T36310	AKT-IN-6	INCB-047775	Akt
	AKT-IN-6 (INCB-047775) has an inhibitory effect on ATK. Akt is an important component of cellular signaling for growth factors, cytokines, and other cell stimuli. Abnormal Akt activation has been associated with the deve...		Akt
TN5131	Tetrahydrocannabivarin	THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin	Cannabinoid Receptor
	Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in ob...		Cannabinoid Receptor
T1627	Famotidine	MK-208	Histamine Receptor
	Famotidine (MK-208) is a propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidi...		Histamine Receptor
T32614	L-Clausenamide	(-)-Clausenamide	Microtubule Associated
	L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents t...		Microtubule Associated
T10109	3-Carene	Delta-3-Carene	COX , Antifungal
	3-Carene（Delta-3-Carene） is a bicyclic monoterpene extracted from western larch and Douglas-fir that acts as a phytofungicide.3-Carene inhibits inflammatory infiltrates and COX-2 overexpression induced by nociceptive sti...		COX , Antifungal
T14198	ALX-1393		GlyT
	ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic cu...		GlyT
T35105	Way 100252	Way-100252,Way100252
	Way 100252 inhibits evoked [3H]GABA release when tested against a number of release-inducing stimuli.
T35082	VU6010608	VU-6010608,VU 6010608
	VU6010608 is an effective mGlu7 NAM with excellent CNS permeability and is powerful in electrophysiological studies in blocking long-term enhancement of high-frequency stimuli.
TP1608	PTD-p65-P1 Peptide
	PTD-p65-P1 Peptide, a selective inhibitor of the nuclear transcription factor NF-kappaB, consists of a conjugation between a membrane-translocating peptide derived from antennapedia (PTD) and p65-P1. This composition eff...
TP1395	PTD-p65-P1 Peptide TFA
	Ptd-p65-p1 Peptide TFA is a nuclear transcription factor nf-kappab inhibitor, consisting of a membrane transport Peptide sequence derived from antennapedia linked to p65-p1, selectively inhibiting nf-kappab activity indu...
T70581	CY208-243 Mandelate
	CY208-243 is a D1 agonist. CY208-243 attenuates the pattern electroretinogram to low spatial frequency stimuli in the monkey. CY208-243 stimulates adenylate cyclase in rat striatal homogenates with an EC50 of 125 nM. CY...
T26807	Bifeprunox Mesylate	Bifeprunox,DU 127090,DU-127090,DU127090
	Bifeprunox is a partial dopamine and serotonin agonist potentially for the treatment of schizophrenia. Bifeprunox suppresses in vivo VTA dopaminergic neuronal activity via D2 and not D3 dopamine autoreceptor activation. ...
TP2176	Amyloid A protein fragment [Homo sapiens]		Others
	Amyloid A proteins (H2N-Ala-Gly-Leu-Pro-Glu-Lys-Tyr-OH) are a family of apolipoproteins associated with high-density lipoprotein in plasma. Different isoforms of SAA are expressed constitutively at different levels or in...		Others
T67212	Ligustrazine HCl
	Ligustrazine Hydrochloride, is a natural substance discovered in the plant Ligusticum chuanxiong Hort. It inhibits platelet aggregation, improves atherosclerosis situation, protects endothelium injury, and has antithromb...