Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 1,380.00 | |
5 mg | In stock | $ 2,800.00 | |
10 mg | In stock | $ 3,780.00 | |
25 mg | In stock | $ 5,620.00 | |
50 mg | In stock | $ 7,590.00 | |
100 mg | In stock | $ 9,870.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 2,880.00 |
Description | ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic currents in the abdominal horn of the spinal cord. Antiinjurious effects on thermal, mechanical and chemical stimuli in rat models of acute pain. |
In vivo | ALX1393 (i.c.v.; 25, 50, and 100 μg) suppresses the late-phase response in the formalin test in normal rats while having no impact on motor performance. Additionally, ALX1393 exhibits dose-dependent inhibition of mechanical and cold hyperalgesia. [1] |
Molecular Weight | 395.42 |
Formula | C23H22FNO4 |
CAS No. | 949164-09-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (27.82 mM)
You can also refer to dose conversion for different animals. More
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ALX-1393 949164-09-4 Neuroscience GlyT ALX1393 ALX 1393 inhibitor inhibit