respiration — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T37657	Mitochondrial respiration-IN-1 hydrobromide
	Mitochondrial respiration-IN-1 hydrobromide (compound 49) is a potent mitochondrial inhibitor (IC50=8.8 mg/mL). Mitochondrial respiration-IN-1 hydrobromide significantly reduces mitochondrial respiration in platelets[1].
T72137	Mitochondrial respiration-IN-3
	Mitochondrial respiration-IN-3, a fluorine derivative of Dalfopristin, possesses cell membrane permeability and exhibits the capability to inhibit mitochondrial translation in glioblastoma stem cells. This compound is ut...
T72138	Mitochondrial respiration-IN-2
	Mitochondrial respiration-IN-2, a fluorine derivative of Virginiamycin M1, inhibits the mitochondrial translation of glioblastoma stem cells [1].
T40247	Ethofumesate		Others
	Ethofumesate is a chiral herbicide. Ethofumesate acts by inhibiting mitosis and reducing photosynthesis and plant respiration.		Others
T9235	GW604714X	2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-	Mitochondrial Metabolism
	GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitochondrial respiration supported by pyruvate		Mitochondrial Metabolism
T77621	Z16078526		p38 MAPK , Mitochondrial Metabolism
	Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes. Additionally, it activates thermogenic gen...		p38 MAPK , Mitochondrial Metabolism
T16470	Penthiopyrad	Vertisan,MTF-753	Antifungal
	Penthiopyrad (MTF-753) shows a broad spectrum of antifungal activity and suppresses fungal respiration. Penthiopyrad can be used in studies about foliar and soil-borne plant diseases.		Antifungal
T9768L	Ninerafaxstat trihydrochloride	Ninerafaxstat trihydrochloride(2254741-41-6 Free base)	Others
	Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation. Ninerafaxstat trihydrochloride improves overall mitochondrial respiration and reduces fatty acid oxidation, thereb...		Others
T7486	Imeglimin hydrochloride	EMD 387008 hydrochloride	Reactive Oxygen Species , Mitochondrial Metabolism
	Imeglimin hydrochloride (EMD 387008 hydrochloride) prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.		Reactive Oxygen Species , Mitochondrial Metabolism
T21275	Azoxystrobin	HSDB 7017,ICI-A 5504,Bankit,ICIA-5504,Amistar	Antifungal
	Azoxystrobin (Bankit) is a broad-spectrum fungicide. Azoxystrobin induces ROS production, cell apoptosis and mitochondrial respiration by blocking electron transfer between cytochromes b and c1.		Antifungal
TN6891	1-Hexanol	hexan-1-ol	Others
	1-Hexanol (hexan-1-ol) is a natural product.1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[1]. 1-Hexanol uncouples mitochondrial respiration b...		Others
T14346	Aumitin		Others , Autophagy
	Aumitin is a diaminopyrimidine-based autophagy inhibitor. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1], and it inhibits mitochondrial re...		Others , Autophagy
T9232	Mitochondrial fusion promoter M1		Mitochondrial Metabolism
	Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...		Mitochondrial Metabolism
T0064	Adenine	Vitamin B4,6-Aminopurine	DNA/RNA Synthesis , Endogenous Metabolite , AChR
	Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic...		DNA/RNA Synthesis , Endogenous Metabolite , AChR
T7028	Licochalcone C	LICOCHALCONEC	Phosphatase , Antioxidant , Glucosidase
	Licochalcone C (LICOCHALCONEC) has potent antioxidant properties and inhibition of bacterial growth and cellular respiration. It has cardioprotection effect, via antioxidant, anti-inflammatory, and anti-apoptotic activit...		Phosphatase , Antioxidant , Glucosidase
T36141	Boscalid		Mitochondrial Metabolism
	Boscalid is a broad-spectrum carboxamide fungicide that inhibits fungal respiration by binding to the ubiquinone site of mitochondrial complex II/succinate dehydrogenase.1It suppresses mycelial growth ofS. minorby 87 to ...		Mitochondrial Metabolism
T10706	CCI-006		Mitochondrial Metabolism
	CCI-006, a selective inhibitor and chemosensitizer for MLL-rearranged leukemia cells, disrupts mitochondrial respiration. This action leads to irreversible mitochondrial depolarization and triggers a pro-apoptotic unfold...		Mitochondrial Metabolism
T27453	GSK1733953A	DG70	Antibacterial
	GSK1733953A can be used as a small molecule Mycobacterium tuberculosis respiration inhibitor with an inhibitory effect on MenG activity and an IC50 value of 2.6 ± 0.6 μM.GSK1733953A is a selective biphenylbenzamide with ...		Antibacterial
T77577	SLU-PP-332		Estrogen/progestogen Receptor
	SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellula...		Estrogen/progestogen Receptor
T1331	Riboflavin phosphate sodium	Riboflavin 5'-phosphate sodium,Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,FMN-Na,riboflavin-5'-phosphate	Endogenous Metabolite
	Riboflavin phosphate sodium (FMN) is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes. Rib...		Endogenous Metabolite