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Search Results for " rectifier "

20

Compounds

Cat No. Product Name Synonyms Targets
T22408 Proflavine 3,6-Diaminoacridine Antibacterial
Proflavine (3,6-Diaminoacridine) (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria and is a topical antiseptic used mainly in wound dressings.
T0438 Proflavine Hemisulfate 3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate Others , Potassium Channel , DNA , Thrombin , Antibacterial , Autophagy
Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and a...
T5585 AM-92016 hydrochloride Potassium Channel
AM-92016 is a specific blocker of rectifier potassium current. AM-92016 delays rectifier potassium channel and repolarizes the membrane thereby restricting the duration of the nerve impulse.
T22745 DPO-1 Potassium Channel
DPO-1 is a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels
T27205 DPI 201-106 DPI-201-106 Sodium Channel
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delayed rectifier potassium currents.
T7505 Azimilide Dihydrochloride NE-10064 Dihydrochloride Potassium Channel
Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current
T8040 Cholesterol myristate Cholesteryl myristate,Cholesteryl tetradecanoate Others , Potassium Channel , GABA Receptor , Endogenous Metabolite , AChR
Cholesterol Myristate (Cholesteryl Myristate) is a natural steroid found in traditional Chinese medicine that interacts with various ion channels, including the GABAA receptor, nicotinic acetylcholine receptor, and the i...
T3574 Sematilide hydrochloride CK-1752A,CK-1752,Sematilide HCl Potassium Channel
Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the ...
T15555 IK1 inhibitor PA-6 Potassium Channel
IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents).
T31011 Coralyne chloride Topoisomerase
Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifier built into DNA duplexes through site-specific insertion. ...
T6476 Dofetilide UK 68789,UK-68798,Tikosyn Potassium Channel
Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik...
T4A2458 Resibufogenin Bufogenin,Recibufogenin Others
1. Resibufogenin (Bufogenin) is a cytotoxic steroid isolated from the Chinese drug ChanSu. 2. Resibufogenin can inhibit rectifier potassium current ( I K ) and transient potassium current ( I A ), it has pathological eff...
T22662 Chromanol 293B Others
slow delayed rectifier K+ current (IKs) blocker
T24948 VU625 VU007625,VU 625,VU 007625,VU-625,VU-007625
VU625 is an effective inhibitor of Aedes aegypti inward rectifier potassium channels.
T5336L Zacopride Racemic zacopride
Zacopride is a selective agonist of inward rectifier potassium current (I K1) channel, inhibiting ventricular arrhythmias without affecting atrial arrhythmias.
T70194 AM92016
AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity.
T15460 Halofantrine hydrochloride WR-171669,SKF-102886 Others
Halofantrine hydrochloride is a blocker of delayed rectifier potassium current. Halofantrine hydrochloride also via the inhibition of the human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial agent.
T14189 Almokalant H 234​/09 Potassium Channel
Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker. And it inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.
T80510 Tertiapin-RQ Potassium Channel
Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1].
T61685 Ibutilide
Ibutilide (U70226E free base) is a potent antiarrhythmic compound that extends the action potential duration. It effectively blocks the rapidly activating delayed rectifier potassium current (I Kr ) in AT-1 cells [1].
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